AI Article Synopsis
- The study investigated how danger (DS) and safety (SS) signals affect brain activity in male rats during a conditioning experiment involving tail-shock.
- The researchers measured local field potentials (LFPs) in hippocampal regions, focusing on theta and delta frequency bands.
- Findings revealed that theta frequency decreased during DS as the trial progressed, with distinct frequency patterns observed in different hippocampal areas during danger vs. safety, indicating varying sensory processing and emotional states.
Article Abstract
The effect of stimuli predicting danger (DS) and safety (SS) in Pavlovian aversive conditioning on hippocampal local field potentials (LFP) was studied in 25 partially restrained adult male rats (Long-Evans). DS lasting 5 s preceded tail-shock, while SS overlapping DS during DS last 3 s predicted omission of shock. The power spectra of LFPs during trials were analyzed in theta and delta frequency bands. In DS, theta frequency during the last 3 s was lower that in first 2 s. In danger and safety situation theta peak frequency was different for dorsal CA1 activity (5.99 Hz vs. 6.86 Hz, respectively) while delta peak frequency was different for ventral CA1 (1.56 Hz vs. 1.07 Hz) for the last 3 s of trial. Differences in theta frequency in danger and safety situation may reflect differences in sensory processing during induced emotional states and/or related differences in motor behavior.
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| http://dx.doi.org/10.55782/ane-2009-1734 | DOI Listing |
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