Thermus thermophilus strains active in purine nucleoside synthesis.

Molecules

Biotransformations Group, Servicio de Biotransformaciones Industriales, Parque Científico de Madrid, C/ Santiago Grisolia n masculine 2, 28760 Tres Cantos, Madrid, Spain.

Published: March 2009

Several strains of Thermus thermophilus were tested in order to detect purine nucleoside synthase activity using pyrimidine nucleosides as the sugar-donor and adenine or hypoxanthine as bases. High productivity values (t =1 hr) were obtained while completely avoiding adenosine-deaminase degradation of the products. N-2-deoxy-ribosyltransferase activity is described for the first time in hyperthermophilic bacteria.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253774PMC
http://dx.doi.org/10.3390/molecules14031279DOI Listing

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