Background: Patients with renal insufficiency represent a difficult group. They show an increased morbidity and mortality after heart surgery. Nondialysis chronic kidney disease patients show higher mortality than patients receiving chronic dialysis. Their management is not standardized. This study was undertaken to determine whether elective perioperative dialysis in these patients improved outcomes.
Method: A retrospective review of records of nondialysis chronic kidney disease patients was carried out. Patients who were not dialyzed before surgery (group A, n = 28) were compared with a propensity-matched group of patients (group B, n = 28) who received elective dialysis preoperatively for their baseline characteristics and outcomes of their heart surgery.
Results: Patients who received elective dialysis in the perioperative period (group B) showed fewer neurologic complications (p = 0.004), shorter postoperative length of stay (p = 0.053), fewer gastrointestinal complications (p = 0.051), and fewer major adverse events (p = 0.013). Multiorgan failure and discharge to an extended care facility were also less frequent in group B, although this did not reach statistical significance.
Conclusions: Nondialysis renal failure patients, particularly those with higher creatinine concentrations, may benefit from elective perioperative dialysis in terms of decreased rates of complications and shorter postoperative length of stay.
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http://dx.doi.org/10.1016/j.athoracsur.2008.12.082 | DOI Listing |
J Perioper Pract
January 2025
Department of Anaethesia, Intensive Care and Pain Management Department, Faculty of Medicine, Assiut University, Assiut, Egypt.
Background: We conducted this study to compare the efficacy of oral 10 and 5 mg olanzapine for the prevention of postoperative nausea and vomiting.
Methods: Notably, 135 female patients between the ages of 18 and 50 years, classed as American Society of Anaesthesiologists I and II, who underwent elective laparoscopic gynaecological surgery under general anaesthesia were randomly assigned to one of three groups (45 each) to receive perioperative 5 or 10 mg oral olanzapine (OL5 and OL10 groups), or a placebo (in the control group). Postoperation, we recorded the occurrence and severity of postoperative nausea and vomiting within 24 h, the number of patients who received antiemetics and any associated side effects.
BMC Med
January 2025
Department of Gynaecology and Obstetrics, Women and Children's Hospital of Chongqing Medical University (Chongqing Health Center for Women and Children), Chongqing, China.
Background: Prospective trial evidence is lacking regarding the application of enhanced recovery after surgery (ERAS) in transvaginal pelvic floor reconstruction surgery among older patients. Our study aimed to investigate whether implementing the ERAS protocol could enhance post-operative recovery in this patient population.
Methods: Older patients undergoing elective transvaginal pelvic floor reconstruction surgery were randomly assigned to either the ERAS group or the conventional group.
Global Spine J
January 2025
Research & Development, Endospine SLU, Andorra la Vella, Andorra.
Study Design: Exploratory prospective observational case-control study.
Objectives: Aim of this study was to compare clinical and radiologic outcome, as well as peri-operative complications, of anterior lumbar interbody fusion (ALIF) and full-endoscopic/percutaneous trans-Kambin transforaminal lumbar interbody fusion (pTLIF) with a large-footprint interbody cage.
Methods: Patients that underwent elective ALIF and pTLIF with a large-footprint interbody cage were prospectively evaluated.
Ann Vasc Surg
January 2025
Department of Vascular Surgery, Centre hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec. Electronic address:
Objectives: Optimal timing for intervention for abdominal aortic aneurysms remains unclear. Given the increased rupture risk with larger aneurysms, timely intervention is critical. This study sought to examine endovascular aortic aneurysm repairs (EVAR) delays across Canadian centers, focusing on potential differences related to geography, sex and race.
View Article and Find Full Text PDFPharmaceuticals (Basel)
December 2024
Department of Anesthesiology and Perioperative Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
The last two decades have provided far more options f both patients and their physicians in the treatment of diabetes mellitus. While dipeptidyl peptidase-4 inhibitors (DPP-4is) and glucagon-like peptide 1 receptor agonists (GLP-1RAs) have been approved for nearly two decades, sodium-glucose cotransporter 2 inhibitors (SGLT-2is) are relatively new. Of interest to perioperative physicians, these drugs present specific perioperative concerns, prompting many societies to issue guidelines.
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