Single-crystal tubular products on the millimetre scale have been synthesized from water-soluble calixarene and phenanthroline in the presence of lanthanides by a hydrothermal method, in which the extended structures contain some 1D infinite channels.
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http://dx.doi.org/10.1039/b821065a | DOI Listing |
Chem Commun (Camb)
January 2025
Center for Supramolecular Chemistry & Catalysis and Department of Chemistry, College of Science, Shanghai University, Shanghai 200444, China.
Macrocyclic structures are popular in supramolecular chemistry and have enjoyed considerable success as platforms for elaboration to container compounds and new materials. Host/guest studies in organic media have relied heavily on structures derived from crown ethers, calixarenes, cucurbiturils, resorcinarenes and pillararenes over the past decades. More recently, their water-soluble versions have been developed for potential applications in biology.
View Article and Find Full Text PDFLangmuir
December 2024
Sao Carlos Institute of Physics, University of Sao Paulo, CP 369, 13560-970 São Carlos, SP, Brazil.
The design of chemotherapeutic drug carriers requires precise information on their interaction with the plasma membrane since the carriers should be internalized by cells without disrupting or compromising the overall integrity of the membrane. In this study, we employ Langmuir monolayers mimicking the outer leaflet of plasma membranes of healthy and cancerous cells to determine the molecular-level interactions with a water-soluble calixarene derivative, -sulfonic acid calix[4]arene (SCX4), which is promising as drug carrier. The cancer membrane models comprised either 40% 1,2-dipalmitoyl--glycero-3-phosphocholine (DPPC) or 1,2-dioleoyl--glycero-3-phosphocholine (DOPC), 30% cholesterol (Chol), 20% 1,2-dipalmitoyl--glycero-3-phosphoethanolamine (DPPE), and 10% 1,2-dipalmitoyl--glycero-3-phospho-l-serine (DPPS).
View Article and Find Full Text PDFPolymers (Basel)
November 2024
Institute of Polymers, Bulgarian Academy of Sciences, Akad. G. Bonchev St., Block 103A, 1113 Sofia, Bulgaria.
Ladder oligomers containing calixarene skeletons in the main chain-calix[4]resorcinarene (CRA) ladder macromolecules with open chain and cyclic macromolecules with double ring-like (Noria-type) topologies-bring particular research attention as functional materials with various applications. However, there is still a remarkable lack of studies into the synthesis of fully water-soluble derivatives of these interesting macromolecules. Research on this topic would allow their bio-based research and application niche to be at least revealed.
View Article and Find Full Text PDFChem Commun (Camb)
August 2024
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an, China.
A new antibacterial system (HG) based on the host-guest chemistry between pillar[5]arene and a zwitterionic guest was fabricated. The HG complex displayed excellent antibacterial and biofilm formation inhibition and dispersal activities against , and MRSA.
View Article and Find Full Text PDFJ Mater Chem B
August 2024
The Institute for Advanced Studies, Hubei Key Lab on Organic and Polymeric Opto-Electronic Materials, Wuhan University, 299 Bayi Road, Wuhan, Hubei 430072, China.
Stimuli-responsive supramolecular chemotherapy, particularly in response to cancer biomarkers, has emerged as a promising strategy to overcome the limitations associated with traditional chemotherapy. Spermine (SPM) is known to be overexpressed in certain cancers. In this study, we introduced a novel supramolecular chemotherapy system triggered by SPM.
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