Background: A critical problem with neuropsychological assessment in children and adolescents with multiple sclerosis (MS) is the absence of a standardized, well-validated neuropsychological battery specifically tailored for detecting disease-related cognitive problems in this age range.
Objective: To develop a Brief Neuropsychological Battery for Children (BNBC) with MS.
Methods: We assessed cognitive functions in 61 patients with childhood and juvenile MS and 58 demographically matched healthy controls through an extensive neuropsychological battery.
Results: In MS patients, we found a proportion of cognitive impairment of 41%. In the BNBC, we included the tests with higher discriminating ability (the Selective Reminding Test, the Symbol Digit Modalities Test, the Trail Making Test, and the Vocabulary test from the Wechsler Intelligence Scale for children). The BNBC yielded a sensitivity of 96% and a specificity of 76%.
Conclusion: Our findings provide preliminary evidence of the usefulness of the BNBC as a screening tool for detecting cognitive impairment in childhood and juvenile MS cases.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/1352458508101950 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Advancing diagnostic consistency: Statistical methods and interrater reliability in neuropsychological assessments with the MNB.
Appl Neuropsychol Adult
January 2025
Jersey Shore University Medical Center, Neuropsychology Rehabilitation Services, Lifespan, Trinton Falls, NJ, USA.
In the field of neuropsychology, the accuracy of neuropsychological data interpretation has significant implications for both research and clinical practice. The process of test interpretation is fraught with challenges, and a lack of consensus among neuropsychologists can lead to discrepancies in assessment outcomes. Smith et al.
View Article and Find Full Text PDFAnterior prefrontal EEG theta activities indicate memory and executive functions in patients with epilepsy.
Epilepsia
January 2025
Brain and Mind Electrophysiology Laboratory, Multimedia Systems Department, BioTechMed Center, Gdansk University of Technology, Gdansk, Poland.
Objective: Cognitive deficits are one of the most debilitating comorbidities in epilepsy and other neurodegenerative, neuropsychiatric, and neurodevelopmental brain disorders. Current diagnostic and therapeutic options are limited and lack objective measures of the underlying neural activities. In this study, electrophysiological biomarkers that reflect cognitive functions in clinically validated batteries were determined to aid diagnosis and treatment in specific brain regions.
View Article and Find Full Text PDFUse of Robust Norming to Create a Sensitive Cognitive Summary Score in De Novo Parkinson's Disease: An Illustrative Example.
Mov Disord
January 2025
Department of Neurology and Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, USA.
Background: Cognitive impairment is common at all stages of Parkinson's disease (PD), but there is no consensus on which neuropsychological tests to use or how to interpret cognitive battery results. A cognitive summary score (CSS) combines the richness of a neuropsychological battery with the simplicity of a single score.
Objective: The objective of this study was to determine whether a CSS created using robust norming can detect early cognitive deficits in de novo, untreated PD.
Eye Movement Desensitization and Reprocessing: Efficacy in Improving Clinical, Neuropsychological, and Quality of Life in Women Victims of Violence.
Womens Health Rep (New Rochelle)
December 2024
Department of Clinical and Health Psychology, Universitat Autònoma de Barcelona, Barcelona, Spain.
Background: The number of female victims of violence has significantly increased in recent years, resulting in physical, mental, and social damage.
Objective: To determine the effectiveness of the eye movement desensitization and reprocessing (EMDR) psychotherapeutic model compared with narrative exposure therapy (NET) as treatments for clinical improvement, neuropsychological outcomes, and quality of life in women who have experienced violence.
Methods: A randomized experimental study was conducted, involving 120 women exposed to physical, psychological, and sexual violence, who were assigned to either an EMDR or NET group.
Obsessive-compulsive personality disorder increases cognitive inflexibility in people with coronary artery disease.
Compr Psychiatry
December 2024
Laboratory of Behavioral Medicine, Neuroscience Institute, Lithuanian University of Health Sciences, Kaunas-Palanga, Lithuania.
Background: Cardiovascular diseases such as coronary artery disease (CAD) have a high prevalence of psychiatric comorbidities, that may impact clinically relevant outcomes (e.g., cognitive impairment and executive dysfunction).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!