[Effect of tannic acid treatment on the physico-chemical properties of glutaraldehyde-fixed bovine jugular vein].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao

Research Center for Cardiovascular Regenerative Medicine of the Ministry of Health, Cardiovascular Institute and Fu Wai Hospital, CAMS and PUMC, Beijing 100037, China.

Published: February 2009

Objective: To evaluate the effects of tannic acid (TA) treatment on the physico-chemical properties of glutaraldehyde (Glut)-fixed bovine jugular vein (BJV).

Methods: Fresh BJVs were treated with Glut or Glut/TA, respectively. The shrinkage temperature, resistance to collagenase or elastase digestion, bio-mechanical properties, and molecular structure of these prepared BJVs were evaluated by Fourier transform infrared spectroscopy.

Results: TA treatment resulted in higher shrinkage temperature (P < 0.01), higher resistance to collagenase or elastase digestion (P < 0.01), slightly increased tensile strength (P < 0.01), and elongation at break (P < 0.05) in Glut/TA BJV walls when compared with those of Glut group. Chemical bonds existed between TA and JBV tissue.

Conclusion: TA treatment can effectively improve the physicochemical properties of Glut-fixed BJVs.

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