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Challenges and prospects in implementing the Generational Endgame policy: Malaysia and global perspectives.
Tob Control
January 2025
Pharmacy Practice Department, International Islamic University Malaysia Kulliyyah of Pharmacy, Kuantan, Malaysia.
In Malaysia, tobacco smoking continues to be one of the leading public health concerns; hence, the tobacco control community aims to see a generation free of tobacco use by 2040. Drafted and presented to the parliament, the Malaysian Control of Smoking Products for Public Health Bill 2022 highlighted the Generational Endgame (GEG) policy, which forbids the use and sale of tobacco products and smoking substances to individuals born on or after 1 January 2007. Stakeholders, including government and non-governmental organisations, policymakers, healthcare professionals, tobacco industry representatives and retailers, have expressed differing opinions indicating non-support of the policy.
View Article and Find Full Text PDFTobacco-free generation: reflecting on progress globally and its potential feasibility in India.
Tob Control
January 2025
Menzies School of Health Research, Charles Darwin University, Casuarina, Northern Territory, Australia.
Tobacco-free generation (TFG) policies, also conceptualised as smoke-free or nicotine-free generation in some geographies, envision the elimination of tobacco use initiation by preventing tobacco sales to generations born after a specified birth date. This cohort-based policy approach eventually aims to phase out tobacco use. This paper defines TFG, reviews its international developments and explores the feasibility of the TFG policy approach in India, considering the country's federal governance structure with health as a state responsibility, within a national policy framework.
View Article and Find Full Text PDFSmoking's pop culture revival is an unwelcome throwback for public health.
BMJ
January 2025
Action on Smoking and Health.
Prognostic Value of Cardiac MRI Late Gadolinium Enhancement Granularity in Participants with Ischemic Cardiomyopathy.
Radiology
January 2025
Université Paris-Cité, Department of Cardiology, University Hospital of Lariboisière, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France.
Background Ischemic late gadolinium enhancement (LGE) assessed with cardiac MRI is a well-established prognosticator in ischemic cardiomyopathy. However, the prognostic value of additional LGE parameters, such as extent, transmurality, location, and associated midwall LGE, remains unclear. Purpose To assess the prognostic value of ischemic LGE features to predict all-cause mortality in ischemic cardiomyopathy.
View Article and Find Full Text PDFChronic nicotine exposure induces molecular and transcriptomic endophenotypes associated with mood and anxiety disorders in a cerebral organoid neurodevelopmental model.
Front Pharmacol
December 2024
Addiction Research Group, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
Introduction: Prenatal nicotine exposure (PNE) from maternal smoking disrupts regulatory processes vital to fetal development. These changes result in long-term behavioral impairments, including mood and anxiety disorders, that manifest later in life. However, the relationship underlying PNE, and the underpinnings of mood and anxiety molecular and transcriptomic phenotypes remains elusive.
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