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Topographic Analysis of the Periorbital Region Including Orbicularis Oculi Muscle Based on Ultrasonography Interpretation.
J Cosmet Dermatol
January 2025
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, South Korea.
Objective: Ultrasonographic examination is easy, fast, safe, and used in various fields; however, its application to the facial area has been limited. Complex anatomical structures are mixed within thin, soft tissues in the facial region; therefore, understanding their structural characteristics is crucial. This study aimed to use ultrasonography to obtain information on the layered structure and soft tissue thickness of the eye area around the orbicularis oculi muscle and provide guidance for clinical practice.
View Article and Find Full Text PDFRapid Manufacturing Method of Cardiovascular Models for Experimental Flow Analysis.
MethodsX
June 2025
Texas A&M University Department of Biomedical Engineering, College Station, TX 77840, US.
Physical anatomical models constructed from medical images are valuable research tools for evaluating patient-specific clinical circumstances. For example, 3D models replicating a patient's internal anatomy in the cardiovascular system can be used to validate Computational Fluid Dynamics (CFD) models, which can then be used to identify potential hemodynamic consequences of surgical decisions by providing insight into how blood and vascular tissue mechanics may contribute to disease progression and post-operative complications. Patient-specific models have been described in the literature; however, rapid prototyping models that achieve anatomical accuracy, optical transparency, and thin-walled compliance in a cost and time-effective approach have proven challenging.
View Article and Find Full Text PDFNeural correlates of facial recognition deficits in autism spectrum disorder: a comprehensive review.
Front Psychiatry
January 2025
School of Education Science, Jiangsu Normal University, Xuzhou, China.
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by significant impairments in social interaction, often manifested in facial recognition deficits. These deficits hinder individuals with ASD from recognizing facial identities and interpreting emotions, further complicating social communication. This review explores the neural mechanisms underlying these deficits, focusing on both functional anomalies and anatomical differences in key brain regions such as the fusiform gyrus (FG), amygdala, superior temporal sulcus (STS), and prefrontal cortex (PFC).
View Article and Find Full Text PDFGenomic and transcriptomic signatures of sequential carcinogenesis from papillary neoplasm to biliary tract cancer.
J Hepatol
January 2025
Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:
Background & Aims: Papillary neoplasms of the biliary tree, including intraductal papillary neoplasms (IPN) and intracholecystic papillary neoplasms (ICPN), are recognized as precancerous lesions. However, the genetic characteristics underlying sequential carcinogenesis remain unclear.
Methods: Whole-exome sequencing was performed on 166 neoplasms (33 intrahepatic IPNs, 44 extrahepatic IPNs, and 89 ICPNs), and 41 associated carcinomas.
From MRI to FEM: an automated pipeline for biomechanical simulations of vertebrae and intervertebral discs.
Front Bioeng Biotechnol
January 2025
Institute for Neuroradiology, TUM University Hospital, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Introduction: Biomechanical simulations can enhance our understanding of spinal disorders. Applied to large cohorts, they can reveal complex mechanisms beyond conventional imaging. Therefore, automating the patient-specific modeling process is essential.
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