AI Article Synopsis

  • IncA/C plasmids in Salmonella enterica serovars Senftenberg and Ohio contain a unique cassette configuration within a class 1 integron, along with five resistance genes (aacC4, aphA1, hph, sul2, and tetA(D)).
  • A deletion in the 5' conserved segment and orfF cassette resulted in an array featuring a partial orfF linked to the aadA2 cassette.
  • While the IncA/C plasmids couldn't be recovered via conjugation, some strains did carry additional conjugative resistance plasmids.

Article Abstract

IncA/C plasmids carrying an unusual cassette configuration in a class 1 integron and five further shared resistance genes, aacC4, aphA1, hph, sul2, and tetA(D) were found in Salmonella enterica serovars Senftenberg and Ohio. A deletion formed using a short region of homology in the 5' conserved segment and the orfF cassette created an array with only part of orfF followed by the aadA2 cassette. The IncA/C plasmids were not recoverable by conjugation, but additional conjugative resistance plasmids were present in some strains.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687259PMC
http://dx.doi.org/10.1128/AAC.00233-09DOI Listing

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