5-Alkyl and aryl-pyrazole-tetrazoles have been identified as a new class of selective, small-molecule, agonists of the human G-protein-coupled receptor GPR109a, a high affinity receptor for the HDL-raising drug nicotinic acid.
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| http://dx.doi.org/10.1016/j.bmcl.2009.03.014 | DOI Listing |
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