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Advancements in prognostic factors and survival outcomes following pulmonary metastasectomy for head and neck cancers.
Kardiochir Torakochirurgia Pol
December 2024
Department of Cardiothoracic and Vascular Surgery, Westpfalz Klinikum, Kaiserslautern, Germany.
Surgical treatment of lung metastases originating from head and neck tumors has shown favorable outcomes with low incidence of complications and mortality. This study aims to investigate survival and prognostic factors following pulmonary metastasectomy for head and neck cancers. A comprehensive review of the literature was conducted through the Medline database, focusing on English-language studies related to surgical treatment of lung metastases from head and neck cancers.
View Article and Find Full Text PDFArthroscopic Suprapectoral Biceps Tenodesis Using an Onlay Technique.
Arthrosc Tech
December 2024
Queensland Unit for Advanced Shoulder Research (QUASR), Queensland University of Technology, Brisbane, Australia.
Tenodesis of the long head of biceps is a common shoulder surgical procedure. Tenodesis can be performed either arthroscopically or open and within the glenohumeral joint, within the bicipital groove, or below the pectoralis major tendon insertion. Arthroscopic tenodesis of the biceps tendon reduces the risk of infection.
View Article and Find Full Text PDFArthroscopic Recognition and Treatment Options for Biceps Subluxation.
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Mississippi Sports Medicine and Orthopaedic Center, Jackson, Mississippi, U.S.A.
Instability of the long head of the biceps tendon is a common pathologic condition that may be difficult to identify using history, physical examination, advanced diagnostic imaging, and even arthroscopic diagnostic inspection. The goal of this technical article is to showcase important anatomic features, intra-articular arthroscopic assessment, and commonly associated pathologies that should raise concern for biceps instability. Techniques to address concurrent biceps and subscapularis lesions are also described.
View Article and Find Full Text PDFEfficacy of metformin and verteporfin treatment alone or in combination in a murine head and neck cancer xenograft model.
Eur J Oral Sci
January 2025
Department of Oral Bioscience and Dental Public Health, International College of Dentistry, Walailak University, Bangkok, Thailand.
Despite treatment advances, head and neck squamous cell carcinoma (HNSCC) still poses a significant global health challenge. Combination therapies have emerged as more effective strategies than traditional chemotherapy in clinical practice by improving tumor response rates and patient survival while minimizing treatment-related toxicity. This study investigates the anticancer effects of metformin and verteporfin (Yes-associated protein 1 [YAP1] inhibitor) alone or in combination in HNSCC using vitro and in vivo approaches.
View Article and Find Full Text PDFModulating tumor-associated macrophages through CSF1R inhibition: a potential therapeutic strategy for HNSCC.
J Transl Med
January 2025
Department of General Surgery of Otorhinolaryngology Head and Neck, The Sixth Affiliated Hospital, Sun Yat-Sen University, No.26, Erheng Road, Yuancun, Tianhe District, Guangzhou, 510655, China.
Purpose: Tumor-associated macrophages (TAMs) are pivotal immune cells within the tumor microenvironment (TME), exhibiting dual roles across various cancer types. Depending on the context, TAMs can either suppress tumor progression and weaken drug sensitivity or facilitate tumor growth and drive therapeutic resistance. This study explores whether targeting TAMs can suppress the progression of head and neck squamous cell carcinoma (HNSCC) and improve the efficacy of chemotherapy.
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