Regarding the treatment of vitally endangered intensive care patients the neuroendocrine regulation of the post-aggression metabolism is important. The role of opioid peptides in this system is investigated in the animal experiment "Haemorrhagic Shock in the Dog". It was shown that the opioid peptide beta-endorphin and metenkephalin rise grossly in connection with pathological and endocrinological alterations in shock. Based on the literature the role of increased concentration of opioids in haemorrhagic shock is discussed and conclusions for therapeutic measures are presented.
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