Seventeen Boeing 737 pilots were exposed to an acute stressor in a flight simulator: a birdstrike between V1 (velocity of aircraft on take-off run at which crew is committed to take-off regardless of any incidents occurring) and VR (velocity of aircraft at take-off). Certain physiological variables together with state anxiety scores were measured at different stages of the simulated flight. Levels of plasma cortisol, norepinephrine, total protein, total lipid, lactate, and the haematocrit changed significantly across the test conditions. Plasma epinephrine, osmolality and glucose levels did not change significantly across the test conditions. Captains and copilots differed significantly in the profiles obtained for the state anxiety scores. The variables measured in this study demonstrated different profiles in response to the stressor. Conceptual and methodological problems need to be solved before an integrated psychophysiological approach to the reactions of pilots to stressors can be developed.
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Nat Commun
January 2025
Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Amsterdam, The Netherlands.
As a result of the current high throughput of the fast fashion collections and the concomitant decrease in product lifetime, we are facing enormous amounts of textile waste. Since textiles are often a blend of multiple fibers (predominantly cotton and polyester) and contain various different components, proper waste management and recycling are challenging. Here, we describe a high-yield process for the sequential chemical recycling of cotton and polyester from mixed waste textiles.
View Article and Find Full Text PDFSci Rep
January 2025
Institute of Emerging Infectious Diseases, Korea University, Seoul, Republic of Korea.
This study aimed to evaluate the usefulness of amplicon-based real-time metagenomic sequencing applied to cerebrospinal fluid (CSF) for identifying the causative agents of bacterial meningitis. We conducted a 16S rRNA amplicon sequencing using a nanopore-based platform, alongside routine polymerase chain reaction (PCR) testing or bacterial culture, to compare its clinical performance in pathogen detection on CSF samples. Among 17 patients, nanopore-based sequencing, multiplex PCR, and bacterial culture detected potential bacterial pathogens in 47.
View Article and Find Full Text PDFPrev Sci
January 2025
Academy of Future Education, Xi'an Jiaotong-Liverpool University, No.8 Chongwen Road, Suzhou, 215123, Jiangsu Province, China.
Parental emotion socialization is crucial to children's development, yet emotion-focused parenting programs are scarce in non-Western contexts. In this study, we developed a four-week emotion-focused parenting program based on the principles of emotion coaching for Chinese families with preschool-aged children. This program integrated parent group sessions with home-based parent-child shared reading.
View Article and Find Full Text PDFInt J Cardiovasc Imaging
January 2025
Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
The use of conventional contrast agents in computed tomography (CT) and magnetic resonance (MR) imaging is often limited in patients with chronic kidney disease (CKD) due to potential nephrotoxicity. Ferumoxytol, originally developed for iron supplementation, has emerged as a promising alternative MR contrast agent that is safer for patients with CKD. This study aims to present our center's experience with ferumoxytol as a contrast agent in CKD patients.
View Article and Find Full Text PDFInfect Dis (Lond)
January 2025
Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, USA.
Background: Whether a detected virus or bacteria is a pathogen that may require treatment, or is merely a commensal 'passenger', remains confusing for many infections. This confusion is likely to increase with the wider use of multi-pathogen PCR.
Objectives: To propose a new statistical procedure to analyse and present data from case-control studies clarifying the probability of causality.
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