Four new xanthones, butyraxanthones A-D (1-4), were isolated from the stem bark of Pentadesma butyracea, together with six known xanthones (5-10) and a triterpenoid (lupeol). The structures of 1-4 were established by spectroscopic methods. Compounds 1-10 were tested in vitro for antiplasmodial activity against a Plasmodium falciparum chloroquine-resistant strain and for cytotoxicity against a human breast cancer cell line (MCF-7). Nearly all of these xanthones exhibited good antiplasmodial activity, and some of them also demonstrated potent cytotoxicity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/np8005953 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Phytochemical Analysis and Antidiarrheal Activity of Stem Bark Decoctions of Sabine (Clusiaceae).
Molecules
December 2024
Institut de Pharmacopée et Médecines Traditionnelles (IPHAMETRA), Centre National de la Recherche Scientifique et Technique (CENAREST), Libreville BP 12 141, Gabon.
is a medicinal plant of which bark decoctions are used in traditional medicine for the treatment of diarrhea symptoms in Gabon. The aim of the present work was to perform phytochemical and pharmacological analyses of decoctions of bark. In a principal approach, spectrophotometric analyses were used to quantify phenolic compounds, followed by liquid chromatography coupled to mass spectrometry analysis that allowed the identification of flavanone-flavone dimers as the main metabolites.
View Article and Find Full Text PDFEvaluation of Yield and Physicochemical Quality of Butter Obtained by Different Traditional Extraction Methods in Ghana.
Int J Food Sci
April 2024
Department of Food Science and Technology, Faculty of Biosciences, College of Science, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
seed butter or fat (PBSB) is a vegetable fat extracted from the seeds of the plant. The butter has potential use in the food, pharmaceutical, and cosmetic industries. The study investigated traditional PBSB processing methods in Ghana and evaluated their effects on yield, physicochemical parameters, and fatty acid composition.
View Article and Find Full Text PDFNew value chain nuts and butter from West Africa to international markets: Biological activities, health benefits, and physicochemical properties.
Food Sci Nutr
February 2024
Laboratory of Human Nutrition and Valorization of Food Bio-Ingredients, Faculty of Agricultural Sciences University of Abomey-Calavi Cotonou Benin.
The tallow or butter tree ( Sabine) is a ligneous forest species of multipurpose use largely distributed in Sub-Sahara Africa. Owing to the biological properties of different parts of the tree and physicochemical properties, as well as the numerous benefits of its fruits, research on products, especially kernels and butter, has now gained more interest. Thus, the scientific literature revealed that butter is a more promising product with good physical and technological characteristics.
View Article and Find Full Text PDFViability of Pentadesma in reduced habitat ecosystems within two climatic regions with fruit harvesting.
J Biol Dyn
December 2022
Department of Mathematics, Prairie View A&M University, Prairie View, TX, USA.
Habitat loss and harvesting of non-timber forest products (NTFPs) significantly affect the population dynamics. In this paper, we propose a general mathematical modelling approach incorporating the impact of habitat size reduction and non-lethal harvesting of NTFP on population dynamics. The model framework integrates experimental data of in Benin.
View Article and Find Full Text PDFPhysicochemical characterization and microbiology quality of the Pentadesma butyracea fruit pulp collected from various parks in Benin.
Sci Rep
August 2021
Laboratoire de Valorisation et de Gestion de la Qualité des Bio ingrédients Alimentaires (LABIO), Faculté des Sciences Agronomiques, Université d'Abomey-Calavi, Jericho, 03 BP 2819, Cotonou, Benin.
In Benin, P. butyracea fruit pulp undergoes significant post-harvest loss due to its low valorization. The collected fruits in five parklands from a survey of transformer's perception were characterized through their visual observations, the determination of their dimensions and pulp proportions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!