Chemical investigation of the leaves of Ilex hainanensis Merr. yielded a new flavanone named Huazhongilexone-7-O-beta-D-glucopyranoside, together with five known compounds, which included caffeic acid, quercetin, isoquercitrin, quercitrin-7-O-beta-D-glucopyranoside and rutin. All of the compounds were isolated from the plant for the first time. The structure of the new compound was determined on the basis of high resolution mass, 1D and 2D NMR spectroscopies including ROESY. The antioxidant activity of the new compound was assessed using the DPPH spectrophotometric and IC(50) value was 10.39 micromol L(-1).
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