On September 29, 2008, the U.S. Department of Homeland Security (DHS) promulgated new regulations streamlining the travel authorization process for people living with HIV wishing to enter the United States as non-immigrants.
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A Digital Approach for a Complete Rehabilitation with Fixed and Removable Prostheses: A Technical Procedure.
Dent J (Basel)
December 2024
Department of Prosthodontics, University of Rennes, 35043 Rennes, France.
The present article describes a step-by-step maximally digitalized workflow protocol with computer-aided design and computer-aided manufacturing (CAD/CAM) in partial-arch edentulous patients rehabilitated with fixed dental prostheses and removable partial dentures (FDPs and RPDs). Facial digitalization, intraoral scans, and functional mandibular movement recordings were used to create a 4D virtual patient on commercially available CAD software. The fixed components including post-and-cores, both metal-ceramic with extra-coronal attachment and monolithic zirconia crowns, and the RPDs were manufactured by computer numerical controlled direct milling.
View Article and Find Full Text PDFA technique to enhance the gingival esthetics of a prototype complete arch fixed implant-supported prototype prosthesis using a 3D printed gingival veneer.
J Prosthet Dent
December 2024
Clinical Professor and Program Director, University of Connecticut Health Center, Farmington, Conn.; and Private practice, Glastonbury, Conn. Electronic address:
An important step in the workflow for a complete arch fixed implant-supported prosthesis is the fabrication of a prototype resin prosthesis to allow the patient to visualize the definitive treatment outcome and also to use as an interim prosthesis. Producing a prototype prosthesis with the natural appearance of the gingival color and contour has been challenging. Current methods include painted stains, manually applied pink composite resin or autopolymerizing acrylic resin, and multicolored resin blocks, but these are all relatively expensive, have less than optimal esthetics, and are labor-intensive and time-consuming.
View Article and Find Full Text PDFDirect covalent attachment of fluorescent molecules on plasma polymerized nanoparticles: a simplified approach for biomedical applications.
J Mater Chem B
January 2025
School of Physics, University of Sydney, Sydney, NSW 2006, Australia.
Polymeric nanoparticles surface functionalised with fluorescent molecules hold significant potential for advancing diagnostics and therapeutic delivery. Despite their promise, challenges persist in achieving robust attachment of fluorescent molecules for real-time tracking. Weak physical adsorption, pH-dependent electrostatic capture, and hydrophobic interactions often fail to achieve stable attachment of fluorescent markers.
View Article and Find Full Text PDFBioinspired Synthesis of (-)-Hunterine A: Deciphering the Key Step in the Biogenetic Pathway.
Chemistry
December 2024
Organocatalysis Research Group, Institute of Organic Chemistry, HUN-REN Research Centre for Natural Sciences, 2. Magyar tudósok krt., H-1117, Budapest, Hungary.
A concise, bioinspired, and enantioselective synthesis of (-)-hunterine A, an odd 6/7/6/6/5 pentacyclic natural product, is described. The key step in the synthesis of this complex structure is an interim-template directed 6-exo selective epoxide ring-opening reaction, which is interwoven with a hydrolysis step of the indolenine hemiaminal template to create the unusual 7-membered azepine bridge motif. Our work not only refines the previously proposed biogenetic pathway, but also reveals the possible stereochemical prerequisite of the unique skeletal rearrangement, which provides a vantage point for understanding how (-)-hunterine A is likely to be generated in nature.
View Article and Find Full Text PDFEvaluating the effectiveness of various agents as interim preservative media for biopsy specimens: An experimental in vitro study.
Saudi Dent J
November 2024
Department of Biomedical Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
In the field of medicine, diagnosing diseases involves various steps, procedures, and protocols. Histopathological examination remains the gold standard for a definitive and accurate diagnosis. This process relies on an initial step of tissue fixation.
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