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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645872 | PMC |
| http://dx.doi.org/10.5489/cuaj.1029 | DOI Listing |
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CAR/CSACI Practice Guidance for Contrast Media Hypersensitivity.
Can Assoc Radiol J
January 2025
Department of Radiology, Dalhousie University, Halifax, NS, Canada.
Contrast media, including iodinated contrast media and gadolinium-based contrast agents, are commonly administered pharmaceuticals with excellent safety profiles. However, a minority of the population may experience a hypersensitivity reaction following intravenous administration. Hypersensitivity reactions can be immediate or delayed, and range from mild, such as urticaria, to severe, including anaphylaxis.
View Article and Find Full Text PDFFracture Risk Assessment in the 2023 Osteoporosis Canada Guideline.
Can Assoc Radiol J
January 2025
Department of Medicine, McGill University, Montreal, QC, Canada.
Radiologists and other diagnostic imaging specialists play a pivotal role in the management of osteoporosis, a highly prevalent condition of reduced bone strength and increased fracture risk. Bone mineral density (BMD) measurement with dual-energy X-ray absorptiometry (DXA) is a critical component of identifying individuals at high risk for fracture. Strategies to prevent fractures are consolidated in the Osteoporosis Canada clinical practice guideline which was updated in 2023.
View Article and Find Full Text PDFCAR Practice Guideline on Bone Mineral Densitometry Reporting: 2024 Update.
Can Assoc Radiol J
January 2025
Division of Nuclear Medicine, St. Paul's Hospital, Vancouver, BC, Canada.
This practice guideline serves as an update to the Canadian Association of Radiologists' 2013 Technical Standards for Bone Mineral Densitometry Reporting. It aims to align bone mineral density testing and reporting practices in Canada with current clinical best practices, including guidelines from Osteoporosis Canada and the International Society for Clinical Densitometry. Key updates include the endorsement of both FRAX and CAROC tools for evaluating fracture risk, guidance for analyzing male patients and transgender patients, and provision of clinical management guidance of relevance to BMD reporting harmonized with that of Osteoporosis Canada.
View Article and Find Full Text PDFEvaluating ADHD medication trial representativeness: a Swedish population-based study comparing hypothetically trial-eligible and trial-ineligible individuals.
Lancet Psychiatry
January 2025
Developmental Evidence synthesis, Prediction, Implementation lab, Centre for Innovation in Mental Health, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK; Hampshire and Isle of Wight NHS Foundation Trust, Southampton, UK; Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK; Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York City, NY, USA; DiMePRe-J-Department of Precision and Regenerative Medicine-Jonic Area, University of Bari Aldo Moro, Bari, Italy.
Background: Randomised controlled trials (RCTs) evaluating ADHD medications often use strict eligibility criteria, potentially limiting generalisability to patients in real-world clinical settings. We aimed to identify the proportion of individuals with ADHD who would be ineligible for medication RCTs and evaluate differences in treatment patterns and clinical and functional outcomes between RCT-eligible and RCT-ineligible individuals.
Methods: We used multiple Swedish national registries to identify individuals with ADHD, aged at least 4 years at the age of diagnosis, initiating pharmacological treatment between Jan 1, 2007, and Dec 31, 2019, with follow-up up to Dec 31, 2020.
Cultural bias in the assessment of language: A closer look at the Boston naming test among multicultural Canadian older adults.
Appl Neuropsychol Adult
January 2025
Neuropsychology and Cognitive Health Program, Baycrest Health Sciences, Toronto, Canada.
Objective: The Boston Naming Test (BNT) is commonly used to assess word-finding in older adults but performance may be impacted by cultural and linguistic factors. This study aimed to assess cultural bias in BNT performance among older adults, explore sources of this bias and provide clinical guidelines for its use in multicultural settings.
Methods: We conducted a retrospective chart review of 525 older adults referred for neuropsychological assessment at a large geriatric hospital in a multicultural Canadian city.
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