Objectives: We evaluated the effectiveness of the Taylor spatial frame (Smith & Nephew, Memphis, TN, USA) in the treatment of complex lower extremity deformities.
Methods: The Taylor spatial frame (TSF) was applied to 29 bone segments of 25 patients (12 females, 13 males; mean age 17 years). Indications for the TSF were congenital disorders (n=12), rickets (n=6), physeal injuries (n=4), stiff nonunions (n=3), malunions (n=3), and sequela from septic arthritis of the knee (n=1). Applications involved the tibia (n=15), femur (n=9), foot (n=4), and knee (n=1) with (n=24) or without (n=5) osteotomies. Following acute correction with the use of the TSF and internal osteosynthesis by plating or nailing, the fixator was removed in six cases. The chronic mode was used in six cases who underwent acute correction. The remaining deformities were gradually corrected using the "total residual mode". The follow-up period ranged from eight months to 42 months (mean 29 months).
Results: The mean duration of external fixator was 24.5 weeks (range 18 to 37 weeks) in 13 tibial and five femoral segments. In all cases, correction was applied until the mechanical axis reached normal limits. Complete consolidation was achieved in all osteotomized segments, including three cases of nonunion. A plantigrade foot was obtained in all foot deformities. Recurrence was seen in one case in which knee contracture and subluxation were treated with soft tissue distraction without osteotomy.
Conclusion: The Taylor spatial frame is a safe and practical method with excellent results in the treatment of nonunions and deformities complicated especially by translation and rotation providing correct clinical data are derived and used.
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http://dx.doi.org/10.3944/AOTT.2009.001 | DOI Listing |
Front Public Health
December 2024
State Key Laboratory of Remote Sensing Science, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China.
Background: Despite examining the role of an association between particulate matter and lung cancer in low-income countries, studies on the association between long-term exposure to particulate matter and lung cancer risk are still contradictory. This study investigates the spatiotemporal distribution patterns of lung cancer incidence and potential association with particulate matter (PM) in Bagmati province, Nepal.
Methods: We performed a spatiotemporal study to analyze the LC - PM association, using LC and annual mean PM concentration data from 2012 to 2021.
Chem Biomed Imaging
December 2024
Experimental Solid State Physics Group, Department of Physics, Imperial College, Exhibition Road, SW72AZ London, U.K.
Mesoporous silica nanoparticles (MSNPs) are promising nanomedicine vehicles due to their biocompatibility and ability to carry large cargoes. It is critical in nanomedicine development to be able to map their uptake in cells, including distinguishing surface associated MSNPs from those that are embedded or internalized into cells. Conventional nanoscale imaging techniques, such as electron and fluorescence microscopies, however, generally require the use of stains and labels to image both the biological material and the nanomedicines, which can interfere with the biological processes at play.
View Article and Find Full Text PDFNat Ecol Evol
December 2024
School of the Environment, University of Queensland, Brisbane, Queensland, Australia.
Accounting for the cost of repairing the degradation of Earth's biosphere is critical to guide conservation and sustainable development decisions. Yet the costs of repairing nature through the recovery of a continental suite of threatened species across their range have never been calculated. We estimated the cost of in situ recovery of nationally listed terrestrial and freshwater threatened species (n = 1,657) across the megadiverse continent of Australia by combining the spatially explicit costs of all strategies required to address species-specific threats.
View Article and Find Full Text PDFHum Brain Mapp
December 2024
Department of Neuroscience, High Resolution Brain Imaging Lab, Baylor College of Medicine, Houston, Texas, USA.
In functional magnetic resonance imaging, the hemodynamic response function (HRF) is a stereotypical response to local changes in cerebral hemodynamics and oxygen metabolism due to briefly (< 4 s) evoked neural activity. Accordingly, the HRF is often used as an impulse response with the assumption of linearity in data analysis. In cognitive aging studies, it has been very common to interpret differences in brain activation as age-related changes in neural activity.
View Article and Find Full Text PDFPLoS One
December 2024
School of Geography, Planning, and Spatial Sciences, University of Tasmania, Hobart, TAS, Australia.
Tropical coral reefs provide a wide range of ecosystem services that benefit millions worldwide. However, the current scale of coral reef restoration is a long way from matching the extent needed to protect coral reefs globally, and this implementation gap presents a complex challenge to overcome. Cross-sectoral collaborative sustainable business models (CSBMs) present an interesting opportunity to scale up coral restoration, though this area is yet to be explored in the literature.
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