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Dramatic response of a gastrointestinal stromal tumor to neadjuvant imatinib therapy. | LitMetric

Gastrointestinal stromal tumors (GISTs) are the most common sarcoma of the alimentary tract and are believed to derive from the interstitial Cell of Cajal. Imatinib mesylate (Gleevec; Novartis, Basel, Switzerland) has revolutionized the treatment of GISTs and is generally used in the metastatic and adjuvant settings. We report the case of a 61-year old man who was treated with neoadjuvant imatinib for a massive gastric GIST with the hope of avoiding a potential multi-visceral resection.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661077PMC
http://dx.doi.org/10.1186/1477-7819-7-30DOI Listing

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