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Web-Based Passive Surveillance: Multifactorial Assessment of Sonali Chicken Diseases and Antimicrobial Prescription Pattern in Bangladesh.
Vet Sci
December 2024
Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Zakir Hossain Road, Khulshi, Chattogram 4225, Bangladesh.
Despite the significant growth in Sonali chicken production across Bangladesh, inadequate disease surveillance and control measures along with indiscriminate antimicrobial use remain major challenges to the sector. In this study, we evaluated the disease burden and antimicrobial prescription patterns of Sonali chickens in Bangladesh using a web-based data recording system from 2020 to 2021 and analyzed 1690 cases. The diagnoses recorded in the system were presumptive, as they were based on clinico-epidemiological history, clinical signs, and gross necropsy findings noted by registered veterinarians.
View Article and Find Full Text PDF2024 analysis of compensation, job duties, and benefits among US shelter medicine veterinarians.
J Am Vet Med Assoc
December 2024
2Veterinary Information Network, Davis, CA.
Objective: To understand the salary, benefits, hours, and job duties of shelter medicine veterinarians.
Methods: Similar to a 2018 survey, an anonymous survey on compensation and duties of shelter medicine veterinarians was conducted via a commercial platform from January 4 to 31, 2024. The survey was distributed through social media, message boards, and specialty listservs.
An application of COM-b model to explore factors influencing veterinarians' antimicrobial prescription behaviors: Findings from a qualitative study in Bangladesh.
PLoS One
December 2024
Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America.
The integration of behavioral theories in designing antimicrobial stewardship (AMS) interventions aimed at optimizing the antimicrobial prescription in veterinary practice is highly recommended. However, little is known about the factors that influence veterinarians' antimicrobial behavior for food-producing animals in lower- and middle-income settings like Bangladesh. There is a large body of research on the factors that influence veterinarian behavior of prescribing antimicrobials, however, there is a need for more studies that use comprehensive behavior change models to develop and evaluate interventions.
View Article and Find Full Text PDFInvestigation of Leptospirosis Agents in Cattle and Humans.
Malays J Med Sci
October 2024
Atatürk University, Faculty of Medicine, Department of Medical Microbiology, Erzurum, Türkiye.
Article Synopsis
- Leptospirosis is a serious zoonotic disease affecting mainly low-income populations, and this study focused on its prevalence in cattle and at-risk human communities in Erzurum, Türkiye.
- Samples from 289 cattle and 100 individuals in high-risk occupations were tested for pathogenic Leptospira serogroups using various laboratory methods like microagglutination testing and PCR.
- Results revealed that 4.5% of cattle tested positive for Leptospira, and there was also a significant presence of antibodies in both high-risk individuals (14%) and a control group (11%), indicating a substantial risk of infection among the general population.
Cryptosporidium PI(4)K inhibitor EDI048 is a gut-restricted parasiticidal agent to treat paediatric enteric cryptosporidiosis.
Nat Microbiol
November 2024
Global Health, Biomedical Research, Novartis, Emeryville, CA, USA.
Diarrhoeal disease caused by Cryptosporidium is a major cause of morbidity and mortality in young and malnourished children from low- and middle-income countries, with no vaccine or effective treatment. Here we describe the discovery of EDI048, a Cryptosporidium PI(4)K inhibitor, designed to be active at the infection site in the gastrointestinal tract and undergo rapid metabolism in the liver. By using mutational analysis and crystal structure, we show that EDI048 binds to highly conserved amino acid residues in the ATP-binding site.
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