Gold nanorod/Fe3O4 nanoparticle "nano-pearl-necklaces" for simultaneous targeting, dual-mode imaging, and photothermal ablation of cancer cells.

Angew Chem Int Ed Engl

Birck Nanotechnology, Bindley Bioscience, and Purdue Cancer Center, Purdue University, 225 S. University Street, West Lafayette, IN 47906, USA.

Published: May 2009

Gold and pearls: Multifunctional nanoparticles, each composed of a single, amine-modified gold nanorod, decorated with multiple "pearls" of Fe(3)O(4) nanoparticles capped with carboxy groups, are prepared. Their effectiveness in simultaneous targeting, dual-mode imaging, and photothermal ablation of breast cancer cells is demonstrated.

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http://dx.doi.org/10.1002/anie.200805282DOI Listing

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