AI Article Synopsis
- A study reviewed 2,267 bone marrows from 2002 to 2005, identifying 322 cases (14%) that met the criteria for inclusion in their research.
- Among these, 73 patients (22.6%) were confirmed to have Myelodysplastic Syndromes (MDS), and 32 (9.9%) had suspected MDS.
- The findings indicate that MDS is more common in older patients, particularly those over 65, and highlights age and specific blood tests as predictive factors, suggesting prevalence in elderly anemic individuals may be higher than previously thought.
Article Abstract
Although unexplained anemia is common in the elderly, the prevalence of MDS is poorly defined. We reviewed 2267 bone marrows reviewed at our center between the years 2002 and 2005. Of these, 322 met our criteria for inclusion (14%). Seventy-three patients (22.6%) had a confirmed diagnosis of MDS and 32 (9.9%) had suspected MDS. Confirmed or suspected MDS was more likely in patients aged >65 (31.5% and 11%, respectively). Age, MCV, LDH and RDW were independently predictive of MDS. Extrapolation of our findings to the elderly anemic individuals in the community suggests MDS prevalence may be higher than previously postulated.
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| http://dx.doi.org/10.1016/j.leukres.2009.02.010 | DOI Listing |
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