AI Article Synopsis
- The study introduces the first successful creation of a beta-C-naphthyl glycoside that can be easily modified into more complex C-aryl glycosides.
- The synthesis process involves a unique hyperbaric HDA reaction using a new type of 2-vinylnaphthalenic dienophile.
- The resulting compound is a (+/-)-beta-C-1,5-dibenzyloxynaphthyl 6,6,6-trifluoro-3-amino glycoside, showcasing potential for further chemical transformations.
Article Abstract
The first de novo synthesis of a beta-C-naphthyl glycoside displaying a convenient functionality for subsequent transformations into complex C-aryl glycosides is reported. The synthesis of this (+/-)-beta-C-1,5-dibenzyloxynaphthyl 6,6,6-trifluoro-3-amino glycoside relies on a hyperbaric HDA reaction involving a new 2-vinylnaphthalenic dienophile.
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