The presence and assortment of 16 known virulence/resistance genetic determinants carried by prophages or prophage-like elements were tested in 212 clinical group A Streptococcus (GAS) strains and related to available data from SmaI macrorestriction/pulsed-field gel electrophoresis analysis and emm typing. A strong correlation existed among the three analyses. This finding supports the substantial contribution to the evolution and diversification of the GAS genome attributed to phages.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681821 | PMC |
| http://dx.doi.org/10.1128/JCM.00925-08 | DOI Listing |
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