A six week clinical surveillance of 163 patients receiving maximally tolerable doses of Asparagus P((R)), a proprietary mixture pulversied dried asparagus root and parsley leaf, has not indicated any clinically useful antihypertensive effect. The profile of adverse events (with 7 patients leaving the surveillance early because of renally related complaints) contraindicates its use in hypertension or to promote flushing of the efferent tract in rental inflammatory conditions or urolithiasis.
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http://dx.doi.org/10.1002/ptr.2787 | DOI Listing |
Probiotics Antimicrob Proteins
January 2025
Home Economic Department, Faculty of Women for Arts Science and Education, Ain Shams University, Cairo, Egypt.
High-fat diet (HFD) consumption disrupts the gut microbiome, instigating metabolic disturbance, brain pathology, and cognitive decline via the gut-brain axis. Probiotic and prebiotic supplementation have been found to improve gut microbiome health, suggesting they could be effective in managing neurodegenerative disorders. This study explored the potential benefits of the probiotic strain Lactobacillus plantarum 20174 (L.
View Article and Find Full Text PDFACS Omega
December 2024
Institute of Agro-product Safety & Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
To investigate the quality and safety difference between agricultural standardization bases and small-scale farmers, we carried out a three-year investigation of asparagus from seven production sites of different sizes in Pinghu city, Zhejiang Province, China, from 2021 to 2023. We documented trace elements (Fe, Zn, Mn, and Cu), quality indicators (vitamin B1, vitamin B2, vitamin C, total sugar, and proteins), and pesticide residues. The evaluation indicated that the quality of asparagus in standardization bases 1-4 was higher than that in small farmer sites 5-7.
View Article and Find Full Text PDFJ Inflamm Res
December 2024
Department of Oncology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Despite advancements in cancer treatment through surgery and drugs, hepatocellular carcinoma (HCC) remains a significant challenge, as reflected by its low survival rates. The mammalian target of rapamycin (mTOR) signaling pathway plays a crucial role in regulating the cell cycle, proliferation, apoptosis, and metabolism. Notably, dysregulation leading to the activation of the mTOR signaling pathway is common in HCC, making it a key focus for in-depth research and a target for current therapeutic strategies.
View Article and Find Full Text PDFBiomed Pharmacother
December 2024
Institute of Brain Science and Disease, Shandong Provincial Collaborative Innovation Center for Neurodegenerative Disorders, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders, Qingdao University, Qingdao 266071, China. Electronic address:
Sci Rep
November 2024
School of Biological Sciences, Universiti Sains Malaysia, 11800, Gelugor, Penang, Malaysia.
Fusarium oxysporum is a cosmopolitan fungus, consisting of both pathogenic and non-pathogenic members and known to be the causative agent of several diseases on various host plants. In Malaysia, most studies have focused on pathogenic F. oxysporum isolates because of their implications for agricultural production, but less attention has been given to non-pathogenic isolates.
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