To evaluate the effect of age and vestibular deficit on the vestibulo-ocular and associated visual reflexes, rotating chair (VOR), eye tracking test (ETT) and optokinetic (OKN) responses were investigated using comparisons between three populations: young normals, vertiginous elderly patients, and age-matched normal elderly subjects. The gain of ETT and OKN responses were reduced for both elderly populations as compared to young normals, but less so for the vertiginous elderly. VOR gain was more significantly reduced in the vertiginous elderly, though VOR time constant was as reduced as for the normal elderly. These results indicate that visual inputs, even in the elderly, are probably employed to compensate for a vestibular deficit.

Download full-text PDF

Source
http://dx.doi.org/10.3109/00016489109131431DOI Listing

Publication Analysis

Top Keywords

vertiginous elderly
12
elderly
8
elderly patients
8
vestibular deficit
8
okn responses
8
young normals
8
normals vertiginous
8
normal elderly
8
elderly vor
8
age visuo-
4

Similar Publications

Article Synopsis
  • This study investigates the use of gait assessment as a non-invasive tool to help diagnose posterior circulation stroke (PCS) in patients experiencing acute dizziness.
  • It analyzed the medical records of 311 vertiginous patients, finding that a significant percentage of those with PCS (95%) showed abnormal gait compared to only 21% in the control group.
  • The results indicate that gait assessment could effectively distinguish PCS cases from non-cases, with high sensitivity and a strong negative predictive value, suggesting further studies are needed for broader validation.
View Article and Find Full Text PDF

Objective: To evaluate the effectiveness of nortriptyline regimen and migraine dietary/lifestyle modifications on dizziness and stress levels in patients diagnosed with vestibular migraine (VM).

Methods: A total of 35 patients diagnosed with definite VM based on the International Classification of Headache Disorders were included in this intervention study. Patients self-selected to receive either nortriptyline regimen alone (10-40 mg daily with biweekly escalation) (group A, n = 17) or migraine dietary/lifestyle modifications alone (group B, n = 18).

View Article and Find Full Text PDF

Misperceptions of subjective visual vertical are associated with poor balance, increasing the risk of falls and accidents. The aim of the present study was to evaluate the effect of nomophobia on verticality perception using subjective visual vertical (S.V.

View Article and Find Full Text PDF

Late-onset Schmidt's Syndrome Presenting with Severe Hyponatremia: A Case Report.

Endocr Metab Immune Disord Drug Targets

July 2024

Unit of Endocrinology, Ospedale Niguarda Ca' Granda, 20162 Milan, Italy.

Article Synopsis
  • - Schmidt's syndrome (SS) is an autoimmune condition that often occurs in young women, where autoimmune thyroiditis (AIT) and autoimmune Addison's disease (aAD) co-occur, sometimes beginning with aAD, as seen in this rare case involving a 73-year-old woman.
  • - The patient arrived at the emergency department with severe symptoms, including hyponatremia (low sodium), which was linked to primary adrenal insufficiency and confirmed through hormone level tests, leading to treatment with hydrocortisone and fludrocortisone.
  • - Careful management of glucocorticoids and fludrocortisone is crucial in elderly patients with heart issues to prevent complications like heart failure, and aAD
View Article and Find Full Text PDF

Objective: To predict one-year seizure freedom, using a combination of relevant clinical variables, following stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy in a series of 101 patients.

Methods: Eight predictors of seizure freedom were selected based on their association with medial temporal lobe epilepsy: (1) MRI evidence of mesial temporal sclerosis (MTS); (2) unitemporal interictal epileptiform discharges; (3) absence of generalized tonic-clonic seizures; (4) history of febrile seizures; (5) onset of epilepsy ≤16 years; (6) absence of an auditory, visual, or vertiginous aura; and (7) unitemporal ictal onset; (8) unitemporal PET hypometabolism. We compared four multivariate models: "MTS," using just evidence of MTS; "FULL," using all eight binary predictors; "AIC" using backwards selection of variables; and "SCORE," using a 0-to-8-point ordinal score awarding one point for each binary predictor.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!