A 47-year-old woman presented with a recurrent nodular lesion on the left upper eyelid that had been resected twice in the previous 5 years. Intraoperative findings showed a thin-walled cystic nodule containing a creamy substance. Histopathology identified steatocystoma; the diagnosis of steatocystoma simplex was further characterized by the absence of a family history and involvement of only one lesion. Steatocystoma is a cystic lesion that is often seen in dermatology practices but that has been reported rarely on the eyelid. Its clinical appearance is indistinguishable from other cystic lesions of the periorbital area and it should be considered in the differential diagnosis of eyelid lesions.
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