Acquired immunodeficiency syndrome (AIDS) is one of the most important infectious diseases threatening the world's population today. The main aim of this study was to assess the epidemiologic features of HIV/AIDS from January 1989 to March 2007 in Hamadan province, Iran. In a cross-sectional study, epidemiodemographic characteristics of HIV/AIDS-positive patients during a period of 17 years were collected from health centers in Hamadan province. This study showed that about 1.8% of HIV/AIDS cases in Iran involved people who lived in Hamadan province. Further study is needed to determine the reasons for this. From January 1989 to March 2007, 285 individuals including 275 males and 10 females were infected with HIV in this province. The study showed that 88% of patients lived in urban areas while 12% involved a rural population. Hamadan city had the highest rate of HIV/AIDS infection and death with 191 and 33 individuals, respectively. The main transmission route was intravenous drug use with 78%. From 28 patients who were entered into the AIDS phase, only 10 patients returned to health centers to be covered under definite treatment. The establishment of the Triangular Clinic can be presented as the starting point in the organization of infected people to detect HIV/AIDS. Altogether, efforts in reducing the impact of HIV in this province to date can be considered beneficial. Continuous laboratory diagnostic strategies may lead in time to therapeutic approaches that result in appropriate outcomes.
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http://dx.doi.org/10.1089/aid.2008.0143 | DOI Listing |
Mol Genet Metab Rep
December 2024
School of Medicine, Urmia University of Medical Sciences, Urmia, West Azerbaijan, Iran.
Objectives: Phenylketonuria is a hereditary condition caused by the deficiency of the enzyme phenylalanine hydroxylase, leading to abnormal phenylalanine metabolism. Managing phenylketonuria involves implementing dietary interventions to control phenylalanine levels and prevent complications. However, these treatments can lead to long-lasting negative effects, including impacts on bone health and abnormal biochemical test findings.
View Article and Find Full Text PDFSci Rep
September 2024
Institut de Biologie Intégrative et des Systèmes, Université Laval Québec, Québec, Canada.
Papaver genus, commonly known as popies, is a valuable source of alkaloids used in medicine, including papaverine, morphine, codeine, and thebaine. We isolated six endophytic fungal isolates producing morphinan alkaloids from four Papaver species growing in Kurdistan Province, Iran. To do this, a 1:1 mixture of methanol and chloroform was used to extract fungal cultures.
View Article and Find Full Text PDFMicrob Pathog
November 2024
Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran; Department of Virology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. Electronic address:
Background: The current study aimed to evaluate the prognostic value of serum amyloid A protein)SAA(protein as a biomarker in diagnosing 2019 novel coronavirus disease)COVID-19(infection.
Methods: The study was conducted on 123 patients with definitive COVID-19 infection referred to Shahid Beheshti and Sina hospitals in Hamedan province, Iran. Five-milliliter blood samples were taken from all included patients and serum was isolated using a centrifuge at 10,000 rpm for 10 min.
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