There has been a paradigm shift from Black's 'extension for prevention' to a minimal intervention approach in the recent time. The most important aspect in diagnosis of earliest stages of enamel demineralization involves accurate and reliable detection of such lesions. The newer diagnostic aids would enable the dentist to detect and diagnose early enamel lesions and direct appropriate preventive measures to promote remineralization and conservation of the tooth substance. A high level of caries experience necessitates preventive strategies which are more cost effective than surgical intervention and restorative procedures.
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J Hum Evol
January 2025
Key Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing 100044, China; CAS Center for Excellence in Life and Paleoenvironment, Beijing 100044, China.
The hominin mandible SK 15 was discovered in April 1949 in Swartkrans Member 2, dated to ∼1.4 Ma. Albeit distorted on the right side, the left and right corpus of SK 15 are relatively low and thick, even compared to most Early to Middle Pleistocene Homo specimens.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, 70124, Italy.
Dental trauma is common in all age groups, although, epidemiologically, it is more common in children with studies that indicate that 15% of preschoolers and 20-25% of school-age children experience it. These injuries, which frequently call for immediate attention, can affect the hard tissues and supporting components of the teeth, and, because dental damage in deciduous teeth occurs frequently and affects speech, nutrition, and oral development, it is particularly worrying. After searching three databases, Scopus, Web of Science (WoS), and PubMed, and removing duplicates, 3,630 articles were screened, and 12 publications were included in the qualitative analysis.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Preventive Dentistry, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Remineralization is a common strategy for the repair of early demineralized tooth enamels, but the harsh dynamic oral environment often hampers its efficacy. Rapid remineralization is expected to address this challenge, however, the stabilizers of remineralization materials often resist their transformation required for repair. Here, by dissolving the ions of calcium and phosphate in glycerol-dominant solvents, we obtain the calcium phosphate clusters (1-2 nm), which are stabilized by glycerol (with high viscosity and affinity to clusters), but can perform a fast enamel repair via the water-triggered transformation in both static and dynamic environments.
View Article and Find Full Text PDFJ Dent Child (Chic)
September 2024
Department of Orthodontics, University of Marburg School of Dentistry, Marburg, Germany.
The purpose of this article is to present three cases of a rare phenomenon called pre-eruptive coronal resorption (PCR), which occurs in teeth with enamel degeneration. In the first case, the enamel defects occurred due to ectodermal dysplasia, which represents the first documented case of a patient with ectodermal dysplasia who underwent PCR. In the other two cases, the enamel defects occurred due to amelogenesis imperfecta.
View Article and Find Full Text PDFJADA Found Sci
November 2024
GreenMark Biomedical Inc, East Lansing and Ann Arbor, MI.
Background: Noninvasive caries treatments work topically, which may limit efficacy. The authors hypothesized that an alternative approach using mineral-loaded particles designed to target the subsurface of noncavitated caries lesions could be advantageous. This study shows in vitro proof-of-concept.
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