[Ventricle-vessels relationship in aspects of hypertension].

Z Gesamte Inn Med

Abteilung für Kardiologie, Fakultät für Medizin, Universität Rostock.

Published: August 1991

The diagnostics of the ventricle-vessel relations in arterial hypertension is significant in particular for advanced stages. Under the aspect to regard the cardiac contraction in form of a model as temporarily varying elastance of the volume invasively (P-measurement, V-measurement, preload alteration via balloon in the inferior vena cava) relations of the ventricular pressure volume (ESPVR, EDPVR) and system-arterial ones in form of the effective arterial elastance can be established. Additionally calculated functional curves give separated information concerning the influence of preload, afterload and contractility on the stroke work. Thus a comprehensive statement concerning the cardiovascular function and a basis for valuable therapeutic effects is worked out. Several references result for advanced stages of the arterial hypertension with hypertrophied heart. The systolic function remains normal for a long time. Diastolically the increasingly disturbed relaxation with pathological preload is found. The relation stroke work-afterload is no more in the optimum region and can further be deteriorated by vasodilation. Whether or not, however, this relation has the same relevance for all clinical questions, remains open. Is the stroke work really that parameter which shall be optimized therapeutically?

Download full-text PDF

Source

Publication Analysis

Top Keywords

arterial hypertension
8
advanced stages
8
stroke work
8
[ventricle-vessels relationship
4
relationship aspects
4
aspects hypertension]
4
hypertension] diagnostics
4
diagnostics ventricle-vessel
4
ventricle-vessel relations
4
relations arterial
4

Similar Publications

Associations of cathepsins with pulmonary arterial hypertension mediated by circulating metabolites: A Mendelian randomization study.

Medicine (Baltimore)

January 2025

National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.

The correlation between cathepsins and pulmonary arterial hypertension (PAH) is well-established, but the causative link between them remains uncertain. This study aimed to explore the causal role of circulating metabolites mediating cathepsins in PAH using Mendelian randomization (MR). A 2-sample 2-step MR method was used to identify causal relationship between cathepsins and PAH; causal relationship between circulating metabolites and PAH; and mediated effects of these circulating metabolites.

View Article and Find Full Text PDF

Background: This study investigates the therapeutic efficacy of dynamic neuromuscular stabilization (DNS) technology paired with Kinesio Taping in patients with persistent nonspecific low back pain, as well as the effect on neuromuscular function and pain self-efficacy.

Methods: A randomized controlled clinical study was conducted to collect clinical data on DNS combined with KT for the treatment of chronic nonspecific low back pain from November 2023 to April 2024. The inclusion criteria were patients with chronic nonspecific lower back pain, aged between 18 and 30 years old, and without serious underlying medical conditions, such as cardiac disease, hypertension, and diabetes.

View Article and Find Full Text PDF

Exploring markers in nursing care of prostate cancer.

Medicine (Baltimore)

January 2025

Urology and Metabolic Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Xixia Zhuang, Badachu, Shijingshan District, Beijing, China.

Prostate cancer is epithelial malignant prostate hyperplasia caused by a tumor. We found prostate cancer GSE141551 and GSE200879 profiles from gene expression omnibus database, followed by differentially expressed genes (DEGs) analysis, weighted gene co-expression network analysis, protein-protein interaction analysis, gene function enrichment analysis, and comparative toxicology database analysis. Finally, the gene expression heat map was drawn, and miRNA information regulating core DEGs was retrieved.

View Article and Find Full Text PDF

The roles of STAT1, CASP8, and MYD88 in the care of ischemic stroke.

Medicine (Baltimore)

January 2025

Nerve Rehabilitation Center, Beijing Rehabilitation Hospital Affiliated to Capital Medical University, Xixia Zhuang, Badachu, Shijingshan District, Beijing, China.

Ischemic stroke is caused by blockage of blood vessels in brain, affecting normal function. The roles of Signal Transformer and Activator of Transcription 1 (STAT1), CASP8, and MYD88 in ischemic stroke and its care are unclear. The ischemic stroke datasets GSE16561 and GSE180470 were found from the Gene Expression Omnibus database.

View Article and Find Full Text PDF

Background: Cardiovascular disease (CVD) morbidity and mortality is increasing in Africa, largely due to undiagnosed and untreated hypertension. Approaches that leverage existing primary health systems could improve hypertension treatment and reduce CVD, but cost-effectiveness is unknown. We evaluated the cost-effectiveness of population-level hypertension screening and implementation of chronic care clinics across eastern, southern, central, and western Africa.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!