Background: A 12-year-old boy presented to a community hospital with fever, malaise and fatigue. A polymerase chain reaction test of the cerebrospinal fluid was positive for Epstein-Barr virus. Despite intensive care treatment and antiviral drugs, the patient died 1 month after his initial presentation.
Investigations: Physical examination, polymerase chain reaction analysis of the cerebrospinal fluid, brain MRI, immunohistochemistry and molecular biological investigations of postmortem brain samples.
Diagnosis: Epstein-Barr Virus encephalitis.
Management: Aciclovir, intensive care treatment with intubation, sedation, antiepileptic drugs.
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| http://dx.doi.org/10.1038/ncpneuro1043 | DOI Listing |
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