In two experiments, we investigated the hypothesis of Rowland and Shanks (2006a) that sequence learning of relevant information is resistant to variations in perceptual load. Under conditions of increased selection difficulty, participants incidentally learned a sequence of targets presented together with three distractors. Target and distractors were composed of pairs of letters and shared more or less features with each other, rendering perceptual identification of the target either more (high load) or less (low load) attention demanding. The expression of sequence learning improved significantly under high load conditions as compared to low load conditions. This could indicate that the cognitive system promotes the development of response-based sequence learning in order to cope with the attentional demands arising from high perceptual load. However, the learning process proved to be unaffected by perceptual load when tested under baseline conditions without distractors (Experiment 1) or under opposite load conditions as during training (Experiment 2). This demonstrates that sequence learning is not influenced by increasing selection demands and suggests that sequence learning runs independently of input attention.
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http://dx.doi.org/10.1027/1618-3169.56.2.84 | DOI Listing |
Cell Div
January 2025
Babak Myeloma Group, Department of Pathophysiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
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View Article and Find Full Text PDFNat Cancer
January 2025
Dept. of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.
The diagnostic landscape of brain tumors integrates comprehensive molecular markers alongside traditional histopathological evaluation. DNA methylation and next-generation sequencing (NGS) have become a cornerstone in central nervous system (CNS) tumor classification. A limiting requirement for NGS and methylation profiling is sufficient DNA quality and quantity, which restrict its feasibility.
View Article and Find Full Text PDFSci Rep
January 2025
The Alan Turing Institute, London, UK.
Air pollution in cities, especially NO, is linked to numerous health problems, ranging from mortality to mental health challenges and attention deficits in children. While cities globally have initiated policies to curtail emissions, real-time monitoring remains challenging due to limited environmental sensors and their inconsistent distribution. This gap hinders the creation of adaptive urban policies that respond to the sequence of events and daily activities affecting pollution in cities.
View Article and Find Full Text PDFBioinformatics
January 2025
School of Computer Science and engineering, Central South University, Changsha, 410083, China.
Motivation: T-cell receptors (TCRs) elicit and mediate the adaptive immune response by recognizing antigenic peptides, a process pivotal for cancer immunotherapy, vaccine design, and autoimmune disease management. Understanding the intricate binding patterns between TCRs and peptides is critical for advancing these clinical applications. While several computational tools have been developed, they neglect the directional semantics inherent in sequence data, which are essential for accurately characterizing TCR-peptide interactions.
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January 2025
GE Healthcare, Guangzhou 510623, China.
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