AI Article Synopsis

  • * An 18F-FDG-PET scan showed significant tumor activity, but bronchoscopy and initial biopsies did not reveal conclusive findings.
  • * Further lung biopsy identified an epithelial granuloma with caseation and confirmed the presence of Mycobacterium intracellulare, highlighting that such nodules, although rare, should be considered in diagnosis despite intense PET uptake.

Article Abstract

A 71-year-old woman with no respiratory symptoms, was admitted because of a solitary pulmonary nodule on a chest radiograph. Computed tomography revealed a 2.0 cm nodule with pleural indentation in the right S2. 18F-fluorodeoxyglucose-positron emission (18F-FDG-PET) showed positive tumor uptake (maximum standardized uptake value = 4.8). Bronchoscopy yielded no specific histological or bacterial findings. Lung biopsy using video-associated thoracoscopy revealed an epithelial granuloma with caseation, but no acid-fast bacilli were detected. PCR revealed Mycobacterium intracellulare (M. intracellulare). A solitary nodule caused by M. intracellulare is rare, but it should be considered in the differential diagnosis even with intense uptake on 18F-FDG-PET.

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