Objective: To establish the optimum preparation and determination method of Liaojin plastics through screening different factors.

Methods: The Orthogonal Test was applied to optimize the best preparation technology, and the content of peoniflorin in Liaojin plastics was determined by HPLC.

Results: The best matrix proportion of plastics was PVA-124 : alcohol : acetone : distilled water = 1 : 4 : 2 : 10; The average recovery of plastics was 98.56%, RSD was 1.66% (n = 9), and the average content of six samples was 0.6817 mg/g, RSD was 1.44%.

Conclusion: The good quality plastics can be produced through this process. HPLC determination method is simple, reliable and can be used in the quality control of Liaojin plastics.

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