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Using 5 alpha reductase inhibitors safely: What primary care physicians need to know.
J Family Med Prim Care
November 2024
Department of Medicine, University of Florida, Gainesville, USA.
5 Alpha Reductase Inhibitor (ARI) is a widely used class of medication; for benign prostatic hypertrophy, androgenetic alopecia and hirsutism. While generally considered safe, ARIs class of medication does have a number of side effects, which can sometimes persist long after discontinuation of the medication. Since this class of medication is generally thought of as being benign, it can be overlooked as a potential cause of new clinical symptoms patients might experience.
View Article and Find Full Text PDFDissecting Cellulitis Presenting After Hair Restoration Surgery.
Cureus
November 2024
Dermatology, Hospital Universitario "Dr. José Eleuterio González", Nuevo León, MEX.
Dissecting cellulitis (DC) of the scalp is a chronic inflammatory condition marked by neutrophilic cicatricial alopecia, often linked to staphylococcal antigens. This case report details a 34-year-old male with scarring acne who developed DC following follicular unit extraction (FUE) approximately four months prior. Trichoscopic examination revealed brown pigmented dots, erythema, and melicerous crusts.
View Article and Find Full Text PDFDifferential expression of androgen receptor and 5-α reductase isoforms in skin cells.
Arch Dermatol Res
December 2024
Epi Biotech Co., Ltd., Incheon, 21983, Republic of Korea.
Non-surgical management of BPH: An updated review of current literature and state of the art on natural compounds and medical therapy.
Arch Ital Urol Androl
December 2024
Casa di Cura Musumeci-Gecas, 95030 Gravina di Catania.
Introduction: Benign prostatic hyperplasia (BPH) is a common urological disease that is strongly associated with the aging process and can lead to lower urinary tract symptoms (LUTS). LUTS due to BPH can significantly affect the quality of life of many patients. Among the treatments available for BPH to improve symptoms and functional outcomes, drug therapy and surgical therapy are the options of choice.
View Article and Find Full Text PDFDual Wavelength LEDs Induce Reactive Oxygen Species and Nitric Oxide That Inhibit the Production of Dihydrotestosterone by 5-α Reductase.
J Biophotonics
December 2024
Revian, Morrisville, North Carolina, USA.
Androgenetic alopecia (AGA) causes balding in approximately 50% of adults. One primary cause of AGA is synthesis of dihydrotestosterone from testosterone by 5-α reductase. Systemic pharmaceutical interventions have potentially serious side effects, necessitating development of localized interventions.
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