An undescribed freshwater fish was recently discovered during a biological inventory of Area de Conservaci6n Guanacaste, northwestern Costa Rica. This new species of Poeciliopsis is closely related to a group of widespread species of small spotted fishes designated as the Poeciliopsis gracilis complex in this study. The complex extends on both versants from southern Mexico to Nicaragua, and with this new finding, extends into Costa Rica. The new species is distinguished from its Central American relatives by its lack of lateral and ventral markings, higher pectoral and caudal-fin counts and more posterior placement of the dorsal fin. Poeciliopsis santaelena is endemic to the Rio Potrero Grande, a river whose flow is reduced to just a few pools during the long dry season and flows fully only during very rainy weather. It is just another in a growing list of threatened or endangered species found in this unique peninsular environment.
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http://dx.doi.org/10.15517/rbt.v56i2.5626 | DOI Listing |
Proc Natl Acad Sci U S A
February 2025
School of Biological Sciences, Life Sciences Department, University of Bristol, Bristol BS8 1TQ, England.
Electric fields in terrestrial environments are used by caterpillars to detect their predators, as foraging cues by pollinators, and facilitate ballooning by spiders. This study shows that electric fields facilitate transportation and detection of hummingbirds in a guild of tropical phoretic mites. Hummingbird flower mites feed on nectar and pollen and complete their life cycle inside flowers.
View Article and Find Full Text PDFPLoS One
January 2025
Departamento de Psicología Evolutiva y Comunicación, Campus Universitario de Vigo, University of Vigo, Vigo, Spain.
The main purpose of this study was to examine the age-related changes in inhibitory control of 450 children at the ages of 7-8, 11-12, and 14-16 when controlling for working memory capacity (WMC) and processing speed to determine whether inhibition is an independent factor far beyond its possible reliance on the other two factors. This examination is important for several reasons. First, empirical evidence about age-related changes of inhibitory control is controversial.
View Article and Find Full Text PDFOncol Res
January 2025
LICIFO, Department of Restorative Sciences, Faculty of Dentistry, University of Costa Rica (HNSCC), San José, 11501, Costa Rica.
The B lymphoma Mo-MLV insertion region 1 homolog (Bmi-1) protein of the polycomb complex is an essential mediator of the epigenetic transcriptional silencing by the chromatin structure. It has been reported to be crucial for homeostasis of the stem cells and tumorigenesis. Though years of investigation have clarified Bmi-1's transcriptional regulation, post-translational modifications, and functions in controlling cellular bioenergetics, pathologies, and DNA damage response, the full potential of this protein with so many diverse roles are still unfulfilled.
View Article and Find Full Text PDFPharmaceutics
January 2025
Programa de Posgrado en Odontología, Universidad de Costa Rica, Ciudad Universitaria Rodrigo Facio, San Jose 11501-2060, Costa Rica.
Objectives: This study aimed to synthesize polylactic acid (PLA) nanofibrillar scaffolds loaded with ibuprofen (IBU) using electrospinning (ES) and air-jet spinning (AJS). The scaffolds were evaluated for their physicochemical properties, drug release profiles, and biocompatibility to assess their potential for local analgesic applications.
Methods: Solutions of 10% (/) PLA combined with IBU at concentrations of 10%, 20%, and 30% were processed into nanofibrillar membranes using ES and AJS.
Pharmaceutics
January 2025
Pharmacy, Pharmaceutical Technology and Physico-Chemical Department, University of Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain.
This study explores the development and characterization of lyophilized chondroitin sulfate (CHON)-loaded solid lipid nanoparticles (SLN) as an innovative platform for advanced drug delivery. Solid lipid nanoparticles are increasingly recognized for their biocompatibility, their ability to encapsulate diverse compounds, their capacity to enhance drug stability, their bioavailability, and their therapeutic efficacy. CHON, a naturally occurring glycosaminoglycan with anti-inflammatory and regenerative properties, was integrated into SLN formulations using the hot microemulsion technique.
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