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[A case of botulism in the Czech Republic and current possibilities for detecting the neurotoxin produced by Clostridium botulinum].
Klin Mikrobiol Infekc Lek
March 2023
Clinic of Infectious Diseases, 1st Faculty of Medicine, UK and Central Military Hospital Prague, Czech Repubic, e-mail:
Article Synopsis
- Botulism is a rare but serious disease in the Czech Republic, with only 155 cases reported since 1960 and just three isolated cases since 2013, aside from one familial instance.
- In July 2022, a couple developed botulism after consuming an untraceable pâté and exhibited neurological symptoms, particularly dysarthria.
- Their condition improved significantly after treatment with antibotulinum serum, and modern techniques like MALDI mass spectrometry were used for diagnosis, avoiding the need for traditional animal testing.
[Functional disorders in patients with lip and nose deformity after cheilorhinoplasty].
Stomatologiia (Mosk)
February 2017
I.M. Sechenov First Moscow Medical University, Moscow, Russia.
Clinical analysis of the nasolabial complex in patients suffering of the unilateral cleft lip and palate deformity after cheilorhinoplasty is presented in the article. Functional disorders such as nasal breathe impairment and it's relation to the nasolabial muscle dystonia in the dependency of primary cheilorhinoplasty type are analyzed. The plan of surgical treatment as well as the postoperative rehabilitation using the botulotoxin injections is offered.
View Article and Find Full Text PDF[The use of tizanidine in combined treatment of arm poststroke spasticity].
Zh Nevrol Psikhiatr Im S S Korsakova
March 2015
Objective: Muscle tone disorders, including poststroke spasticity, is a frequent cause of disability. We studied the efficacy and safety of tizalud (tizanidine) in patients with arm poststroke spasticity.
Material And Methods: Forty-four patients were treated with tizalud and botulotoxin A in different doses in complex with rehabilitation measures or without them.
[The use of different doses of botulotoxin A in the treatment of early arm poststroke spasticity].
Zh Nevrol Psikhiatr Im S S Korsakova
March 2015
Objective: Local injections of botulinum toxin type A (BTA) are currently used in treatment of poststroke spasticity. We assessed the efficacy of botulinum treatment using different doses of BTA.
Material And Methods: We studied 68 patients with early arm poststroke spasticity in the acute and early recovery stages of stroke (up to 3 months from disease onset), mean age of the patients was 60,3±11,4 years.
[Pathophysiological aspects of the use of botulinum toxin dysport in the upper motor neuron lesion].
Zh Nevrol Psikhiatr Im S S Korsakova
April 2016
The most frequent causes of disability of patients with neurological diseases are motor disorders in the upper motor neuron lesion caused by the damage of the brain and/or the spinal cord that resulted in the formation of spastic paresis and paralysis. The correct understanding of the pathophysiological basis of clinical presentations of the upper motor neuron lesion will allow to chose the most adequate and prognostically successful methods of treatment. Currently, treatment with botulotoxin can be considered as such a method.
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