Phytoecdysteroid glycosides (1-5) and a phenylpropanoid ester of sucrose (6) were isolated from the whole plant of Froelichia floridana, along with eight known compounds including three ecdysteroids (7-9), four flavonoids (10-13), and one phenolic compound (14). Structures were determined using a combination of spectroscopic techniques. Compounds 1, 2 and 6-14 were tested in vitro for their activity against human DNA topoisomerase I. Compound 13 (diosmetin) showed marginal inhibition against topoisomerase I with IC(50) of 130 microM in conjunction with low intercalation ability.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.phytochem.2009.01.017 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Lignin Metabolism Is Crucial in the Plant Responses to (Shen) in L.
Plants (Basel)
January 2025
Key Laboratory of Tea Quality and Safety Control, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China.
(Shen) (Hemiptera: Cicadellidae) is a devastating insect pest species of , significantly affecting the yield and quality of tea. Due to growing concerns over the irrational use of insecticides and associated food safety, it is crucial to better understand the innate resistance mechanism of tea trees to . This study aims to explore the responses of tea trees to different levels of infestation.
View Article and Find Full Text PDFPhytochemical analysis of dried ginger extract and its inhibitory effect and mechanism on and associated ureases.
Food Funct
January 2025
Department of Pharmacology, Zunyi Medical University, Zhuhai Campus, Zhuhai 519041, PR China.
(), one of the most common infectious pathogens in the world, can cause gastritis, digestive ulcers, and even gastric cancer. urease (HPU) is a distinctive virulence factor of that allows it to be distinguished from other pathogens. Dried ginger is a famous edible and medicinal herb that is commonly used to prevent and treat gastrointestinal tract-related diseases.
View Article and Find Full Text PDFDifferential impact of impaired steryl ester biosynthesis on the metabolome of tomato fruits and seeds.
Physiol Plant
December 2024
Plant Synthetic Biology and Metabolic Engineering Program, Centre for Research in Agricultural Genomics (CRAG), CSIC-IRTA-UAB-UB, Cerdanyola, Barcelona, Spain.
Steryl esters (SE) are a storage pool of sterols that accumulates in cytoplasmic lipid droplets and helps to maintain plasma membrane sterol homeostasis throughout plant growth and development. Ester formation in plant SE is catalyzed by phospholipid:sterol acyltransferase (PSAT) and acyl-CoA:sterol acyltransferase (ASAT), which transfer long-chain fatty acid groups to free sterols from phospholipids and acyl-CoA, respectively. Comparative mass spectrometry-based metabolomic analysis between ripe fruits and seeds of a tomato (Solanum lycopersicum cv Micro-Tom) mutant lacking functional PSAT and ASAT enzymes (slasat1xslpsat1) shows that disruption of SE biosynthesis has a differential impact on the metabolome of these organs, including changes in the composition of free and glycosylated sterols.
View Article and Find Full Text PDFIdentification of osmotic stress resistance mediated by in apple.
Front Plant Sci
December 2024
Xinjiang Production and Construction Corps, Shihezi University, Shihezi, China.
KAR (Karrikin), a novel plant growth regulator, can be recognized specifically by plants and can activate resistance responses. MdKAI2 is the natural receptor of KARs in apple. Here, we report the identification of osmotic stress resistance in via the method of genetic transformation.
View Article and Find Full Text PDFPoplar Leaf Bud Resin Metabolomics: Seasonal Profiling of Leaf Bud Chemistry in Populus trichocarpa Provides Insight Into Resin Biosynthesis.
Plant Cell Physiol
December 2024
Centre for Forest Biology & Department of Biology, University of Victoria, 3800 Finnerty Road, Victoria, British Columbia, V8P 5C2, Canada.
Trees in the genus Populus synthesize sticky and fragrant resins to protect dormant leaf buds during winter. These resins contain diverse phenolic metabolites, in particular hydroxycinnamate esters and methylated flavonoids. P.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!