Chiral allenamides are prepared with high levels of enantiomeric purity by [2,3]-sigmatropic rearrangement of propargylic sulfimides. The required branched propargylic sulfides are prepared by an enantioselective organocatalytic aldehyde alpha-sulfenylation followed by Corey-Fuchs alkynylation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol900146s | DOI Listing |
Publication Analysis
Top Keywords
[23]-sigmatropic rearrangement
8
enantioselective synthesis
4
synthesis allenamides
4
allenamides sulfimide
4
sulfimide [23]-sigmatropic
4
rearrangement chiral
4
chiral allenamides
4
allenamides prepared
4
prepared high
4
high levels
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!