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Opsoclonus-Myoclonus-Ataxia Syndrome: A Rare Outcome Following Routine Vaccinations.
Cureus
November 2024
Neuropediatrics, Centre for Child Development, Hospital Pediátrico, Unidade Local de Saúde de Coimbra, Coimbra, PRT.
Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare neurological disorder, affecting approximately 0.18 per million individuals annually. It presents with a triad of opsoclonus, myoclonus, and ataxia, often including cognitive dysfunction and behavioral disturbances.
View Article and Find Full Text PDFParaneoplastic Syndromes of the Nervous System in Patients Suffering from SCLC. A Review of the Recent Literature.
Acta Med Acad
August 2024
Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Background: Paraneoplastic Neurological Syndromes (PNS) constitute a heterogeneous cluster of disease manifestations related to various cancers. Small Cell Lung Cancer (SCLC) is strongly related to PNS. This narrative review conducted a survey in the available PubMed literature to highlight the appearance of PNSs in SCLC cases and discuss published research highlights on the subject so that general practitioners can be acquainted with the medical phenomenon present in SCLC patients.
View Article and Find Full Text PDFExploring the Symptoms of and Insights Into Idiopathic Opsoclonus-Myoclonus-Ataxia Syndrome in Adults.
Cureus
October 2024
Neurology, Hospital San Juan de Dios, San José, CRI.
Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare immunological central nervous system disorder that mostly affects children, and it is extremely uncommon in adults. It usually presents idiopathically, as a parainfectious condition, or as a paraneoplastic syndrome. We present a case of a patient who developed adult-onset opsoclonus-myoclonus-ataxia syndrome (OMAS) without any associated infectious or neoplastic disease, a condition that is considered very rare in Central America.
View Article and Find Full Text PDFImmune-mediated neurological syndromes associated with childhood cancers.
Eur J Paediatr Neurol
November 2024
Children's Neurosciences, Evelina London Children's Hospital at Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; Department Women and Children's Health, School of Life Course Sciences (SoLCS), King's College, London, United Kingdom. Electronic address:
Article Synopsis
- The review discusses the link between neurological conditions and underlying cancers, focusing on genetic, environmental, and tumor-related factors that can lead to autoimmunity and paraneoplastic syndromes.
- It covers the pathogenesis of specific paraneoplastic conditions in children, such as Opsoclonus myoclonus ataxia syndrome and NMDA receptor encephalitis, along with current treatment strategies.
- The text highlights advancements in cancer therapies, particularly immune treatments, and examines their potential neurological side effects, emphasizing the need to balance risks and benefits.
Unique Magnetic Resonance Imaging Findings in Opsoclonus-Myoclonus Syndrome Secondary to the West Nile Virus.
Cureus
August 2024
Radiology, Saint Louis University School of Medicine, Saint Louis, USA.
Article Synopsis
- Opsoclonus-Myoclonus syndrome is a rare neurological condition characterized by eye movement issues and can be triggered by infections, like West Nile virus (WNV).
- A 61-year-old male experienced symptoms such as fatigue, lack of coordination, and fever after visiting a cabin during summer, leading to further investigation.
- MRI results showed specific brain changes, and tests confirmed WNV infection, highlighting the significance of neuroimaging in diagnosing cases of encephalopathy amid other health issues.
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