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http://dx.doi.org/10.1007/s00415-009-5055-0 | DOI Listing |
Medicine (Baltimore)
November 2020
Department of Neurology, The Affiliated Hefei Hospital of Anhui Medical University, Hefei, Anhui, P.R. China.
Rationale: Fungal endocarditis (FE) is a rare disease, in which antifungal treatment is necessary. When FE is complicated with prosthetic heart valve and/or atrial fibrillation, the coadministration of antifungal agents and warfarin is inevitable. We report a case of rheumatic heart disease with atrial fibrillation who developed FE following prosthetic heart valve replacement.
View Article and Find Full Text PDFHandb Clin Neurol
December 2010
Department of Health Research & Policy (Epidemiology) and Neurology & Neurological Sciences, Stanford University, Stanford, CA 94305-5405, USA.
Studies of alexia and agraphia have played important roles in understanding how complex cognitive functions are related to brain structure and activity. Modern interests in brain-behavior relations began during the second half of the 19th century as an outgrowth of flawed correlative studies by neuroanatomist Franz Gall and subsequent clinical-pathological analyses by Jean-Baptiste Boulliaud on speech and the frontal lobes. In 1856, Louis Victor Marcé drew attention to writing disorders and postulated a cerebral faculty for writing.
View Article and Find Full Text PDFClin Neurol Neurosurg
July 2001
Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, PA, USA.
Aphemia is a disorder with prominent speech abnormality. Since its description by Broca, there has been debate regarding the neuropsychological disorganization underlying aphemia: is aphemia an articulatory disorder or a language disorder? We describe a patient with markedly impaired articulation, but preserved receptive and written language function and buccal-facial coordination. The location of his stroke was in the left precentral gyrus, undercutting a small area of motor and premotor cortex.
View Article and Find Full Text PDFBrain Inj
May 1989
Department of Speech and Hearing, University of Queensland, St. Lucia, Australia.
A case is presented of a 13-year-old right-handed male who exhibited bilateral striato-capsular lesions following an episode of cerebral anoxia and a range of clinical features typical of aphemia. The findings of a neurological assessment, neuroradiological assessment and battery of speech/language tests are described and their implications for current theories regarding the role of the basal ganglia in speech/language function discussed. The patient initially demonstrated an isolated loss of the ability to articulate words without the loss of the ability to write or comprehend spoken language.
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