Cognitive neurosciences are interested in the concept of self, resulting from two muddled aspects. This concept relates to both a set of personal complex and multidimensional mental representations about ourselves and the flow of self-consciousness which is associated. It grounds individual identity and is related to the subjectivity of the personal experiences, at the core of continuity over the time. The existence of others seems essential in the construction of self mental representations; that is why the concept of self is strongly related to the theory of mind (ToM). ToM corresponds to the capacity to infer representations or mental states to others. Even if self and ToM researches are often carried out in two distinct fields, it seems like these two concepts share common processes. Recent imaging studies comfort this idea. Activations in a common neuronal network (principally median prefrontal cortex and precuneus) were found during the realization of self or ToM tasks. Thus, our capacity to represent our thoughts and others' one coud have a similar cerebral origin. Self-consciousness and consciousness of others could then be considered as a bidirectional interaction at the very bases of both individual identity and the other's knowledge, which regulate behavior and social interactions.
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http://dx.doi.org/10.1684/pnv.2009.0163 | DOI Listing |
J Med Internet Res
January 2025
AIMS Lab, Center for Neurosciences, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
Background: Cognitive deterioration is common in multiple sclerosis (MS) and requires regular follow-up. Currently, cognitive status is measured in clinical practice using paper-and-pencil tests, which are both time-consuming and costly. Remote monitoring of cognitive status could offer a solution because previous studies on telemedicine tools have proved its feasibility and acceptance among people with MS.
View Article and Find Full Text PDFBrain Behav
January 2025
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
Introduction: Patients with bipolar disorder (BD) demonstrate episodic memory deficits, which may be hippocampal-dependent and may be attenuated in lithium responders. Induced pluripotent stem cell-derived CA3 pyramidal cell-like neurons show significant hyperexcitability in lithium-responsive BD patients, while lithium nonresponders show marked variance in hyperexcitability. We hypothesize that this variable excitability will impair episodic memory recall, as assessed by cued retrieval (pattern completion) within a computational model of the hippocampal CA3.
View Article and Find Full Text PDFRes Child Adolesc Psychopathol
January 2025
Department of Psychology and Neuroscience, Temple University, 1701 N. 13th St, Philadelphia, PA, 19122, USA.
Parental depression is associated with offspring depression and sleep problems are prospectively associated with the development of depression. However, little work has examined sleep problems in the offspring of depressed parents and whether these problems partially account for the association between parent and offspring depression. This longitudinal study examined the indirect effect of sleep problems on the association between parent psychopathology and offspring depression in a sample of 10,953 10 to 12-year-old children participating in the Adolescent Brain and Cognitive Development (ABCD) study.
View Article and Find Full Text PDFMov Disord
January 2025
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Objective: Pathogenic variants in B-cell receptor-associated protein (BCAP31) are associated with X-linked, deafness, dystonia and cerebral hypomyelination (DDCH) syndrome. DDCH is congenital and non-progressive, featuring severe intellectual disability (ID), variable dysmorphism, and sometimes associated with shortened survival. BCAP31 encodes one of the most abundant chaperones, with several functions including acting as a negative regulator of endoplasmic reticulum (ER) calcium ion (Ca) concentration.
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