Odour properties of some 5-alkoxy and 5-aryloxymethylene-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ones.

Synopsis The synthesis of 5-alkoxy and 5-aryloxymethylene-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ones by reaction of (+)-5-hydroxymethylene-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-one with a number of saturated or unsaturated alcohols and phenols in order to check how substituents affected the fragrance, is described. Materials and methods for the synthesis of fifteen terpenyl ethers are illustrated. The terpenyl ethers have been tested for their olfactive character and the preliminary findings seem to indicate that some aliphatic ethers showed interesting notes such as floral aroma, honey like aroma, green floral note. Yields, bps or mp, IR and (1)H-NMR spectral data of all compounds are reported.