The Ross procedure is occasionally favoured in young adults, with the implantation of a mechanical conduit remaining a competing option when simultaneous replacement of the ascending aorta is indicated. Eighteen patients with replacement of the ascending aorta, in addition to the Ross procedure (Ross), and 20 patients with a mechanical composite graft (composite) were compared retrospectively. The Short Form Health Survey (SF36) was used to assess quality of life (QoL). There was one death due to ischemic heart disease (composite), and one reoperation due to progressive autograft regurgitation (Ross). Autografts had pressure gradients of 3.1 +/- 1.9 mmHg (versus 10.8 +/- 2.7 mmHg composite; P < 0.001), and 7 autografts showed mild regurgitation. LV mass and global LV function were comparable in both groups (mean EF, 65.5% in Ross versus 61.6 +/- 10.4% in composite, P = NS). Four allografts in a pulmonary position had mild regurgitation (Ross). Two allografts had mild to moderate, and one had moderate pressure gradients (mean, 14.4 mmHg). Patients in the composite group had higher SF36 scores indicating superior QoL. No major bleeding was noted throughout the follow-up period. Despite pre-OP diminished LV function, similar follow-up values and, surprisingly, a higher QoL outcome, favoured the implantation of mechanical conduits in our group. These results warrant further evaluation in larger patient cohorts.
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http://dx.doi.org/10.1536/ihj.50.47 | DOI Listing |
Haemophilia
December 2024
Advanced Center for Oncology, Hematology and Rare Disorders (ACOHRD), K.J. Somaiya Super Speciality Hospital & Research Center, Somaiya Ayurvihar, Sion East, Mumbai, Maharashtra, India.
Introduction: Mortality and morbidity in persons with haemophilia (PWH) have decreased due to improved diagnosis and treatment along with comprehensive population outreach efforts, but the impact is not uniform in different countries.
Aim: The study aims to assess all-cause and intracranial haemorrhage (ICH)-specific mortality of PWH in India.
Methods: This is a retrospective, observational, multi-centric cohort study of 1020 haemophilia patients from three centres in India.
Disabil Rehabil
December 2024
Department of Physiotherapy, Epworth HealthCare, Melbourne, Australia.
Purpose: To investigate the relationship between the distribution and severity of hypertonicity and spasticity on walking speed in people with neurological injuries.
Material/methods: This cross-sectional observation cohort study used the Modified Ashworth Scale (MAS) and Modified Tardieu Scale (MTS) to assess hypertonicity and spasticity of the gastrocnemius, soleus, hamstrings and quadriceps. Participants were classified as having a distal (gastrocnemius and/or soleus), proximal (hamstrings and/or quadriceps) or mixed distribution of hypertonicity or spasticity.
Clin Ophthalmol
December 2024
Department of Ophthalmology, Visual and Anatomical Sciences, Kresge Eye Institute/Wayne State University School of Medicine, Detroit, MI, USA.
Purpose: To evaluate the outcomes of scleral-fixated intraocular lenses (IOLs) implanted using either Yamane technique or Gore-Tex suture fixation, in comparison to intracapsular lens fixation, and to assess the efficacy of various lens formulas in achieving predicted refractive targets.
Patients And Methods: This study included 45 eyes from 44 patients with scleral-fixated IOLs, comprising 37 Yamane eyes and 8 Gore-Tex eyes. Preoperative refractive predictions from various formulae were compared with final postoperative refraction.
CJC Open
December 2024
University Health Network, Toronto, Ontario, Canada.
Background: Patients with heart failure (HF) can experience a poor quality-of-life (QOL), recurring hospitalizations, and progressive disease symptoms. Patient-reported outcome measures (PROMs) integrate patients' voices into clinical care, by assessing patient symptoms, function, and QOL. In 2022, PROMs were incorporated into the electronic health record system (Epic) at a large academic hospital in Toronto, Ontario, Canada.
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December 2024
Ted Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Background: The Weeneebayko Area Health Authority (WAHA) is a regional, community-based Indigenous health authority in Northern Ontario, Canada. From September 2022 to March 2023, the WAHA and University Health Network engaged in a partnership that designed a collaborative model of care to address inequities in cardiology specialist access in Northern Ontario. This model implemented a digital therapeutic for heart failure, (the Medly program) and in-person cardiology clinics in the region.
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