Objectives: The aim of this study was to extend the description of the epidemiologic pattern of human immunodeficiency virus (HIV)/tuberculosis (TB) coinfection from 1998 to 2007 in a high HIV/AIDS prevalence country.
Design And Methods: This study utilized registry data to determine yearly TB incidence and HIV coinfection. Mortality rates for coinfected patients were calculated and compared with patients receiving highly active antiretroviral therapy (HAART).
Results: From a TB population of 2010 registered patients, data was collected on the 466 patients with HIV/TB coinfection. The coinfection rate was found to be 23.6% for the study period. Patients on HAART were twice as likely to survive.
Discussion And Conclusions: The incidence of TB and HIV/TB coinfection rates continues to be major challenges in the developing world. Demographic, socioeconomic trends as well as risk factors remain unchanged. Increased HIV screening and HAART coverage offers hope for the future.
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http://dx.doi.org/10.1177/1545109709331471 | DOI Listing |
Open Forum Infect Dis
January 2025
Division of Infectious Disease, University of Rochester Medical Center, Rochester, New York, USA.
Pancreatic tuberculosis (TB) is an uncommon extrapulmonary presentation of TB. Identification of coinfection with HIV may unmask not only disseminated TB but also immune reconstitution inflammatory syndrome (IRIS). We present the case of a 70-year-old Indian woman newly diagnosed with AIDS and pancreatic tuberculosis with miliary disseminated disease.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Medical Laboratory Science, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Background: HIV-TB co-infection poses a significant public health threat, notably in sub-Saharan Africa including Ethiopia. Despite this public health problem, studies in Ethiopia regarding the mortality of HIV-TB co-infection patients have been inconsistent, and the overall estimate of mortality was not determined. Accordingly, this meta-analysis aims to assess the magnitude of mortality and predictors among HIV-TB co-infected patients in Ethiopia.
View Article and Find Full Text PDFFront Reprod Health
December 2024
Cell Biology Research Platform, Jinan Microecological Biomedicine Shandong Laboratory, Jinan, Shandong, China.
Objective: To assess sex, age, regional differences, and the changing trend in human immunodeficiency virus and tuberculosis (HIV-TB) in different regions from 1990 to 2021, and project future trends.
Methods: Global Burden of Disease Study 2021 data were analyzed to assess HIV-TB incidence, death, prevalence, and DALY rates from 1990 to 2021, including different types of TB co-infections (drug-susceptible, multidrug-resistant, and extensively drug-resistant). Bayesian age-period-cohort models were used to forecast age-standardized DALY rates through 2035.
Immunotargets Ther
December 2024
Pennsylvania State University Hershey Medical Center, 500 University Dr, Heshey, PA, USA.
PLoS One
December 2024
Department of Mathematical Sciences, College of Science, Engineering and Technology, University of South Africa, South Africa.
The co-epidemics of HIV/AIDS and Tuberculosis (TB) outbreak is one of a serious disease in Ethiopia that demands integrative approaches to combat its transmission. In contrast, epidemiological co-infection models often considered a single latent case and recovered individuals with TB. To bridge this gap, we presented a new optimal HIV-TB co-infection model that considers both high risk and low risk latent TB cases with taking into account preventive efforts of both HIV and TB diseases, case finding for TB and HIV/AIDS treatment.
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