AI Article Synopsis
- The study aimed to explore the link between cognitive impairment and the rate of foot ulcers relapsing in diabetic patients with a history of such ulcers.
- The research involved assessing cognitive abilities in 59 diabetic patients over the course of a year and found that cognitive function was not a significant predictor for developing new foot ulcers.
- Overall, the findings suggest that cognitive impairment does not play a major role in the recurrence of foot ulcers among these patients.
Article Abstract
Objective: To study whether there is an association between cognitive impairment and the relapse rate of foot ulcers in diabetic patients and those with previous foot ulcers.
Research Design And Methods: This single-center prospective study assessed the association of cognitive function and risk for ulcer relapse in 59 patients with diabetes (mean age 65.1 years, diabetes duration 16.5 years, and A1C 7.4%), peripheral neuropathy, and a history of foot ulceration. Premorbid and current cognitive functions were measured (multiple-choice vocabulary test [Lehrl], number-symbol test, mosaic test [HAWIE-R], and trail-making tests A and B [Reitan]). Prevalence of depression was evaluated retrospectively (diagnoses in patient files or use of antidepressive medication). Patients were re-examined after 1 year.
Results: Three patients (5%) died during follow-up (one of sepsis and two of heart problems). The remaining 56 patients (48%) developed 27 new foot ulcerations (78% superficial ulcerations [Wagner stage 1]). Characteristics of patients with and without ulcer relapse were not different. In a binary logistic regression analysis, cognitive function is not predictive of foot reulceration.
Conclusions: Cognitive function is not an important determinant of foot reulceration.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671092 | PMC |
| http://dx.doi.org/10.2337/dc08-0490 | DOI Listing |
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