AI Article Synopsis
- Cefoperazone is a third-generation cephalosporin antibiotic effective against various Gram-positive and Gram-negative bacteria.
- It can lead to hypoprotrombinaemia and associated bleeding issues, especially in patients with certain conditions.
- A case is presented of a nine-year-old with Meckel's diverticulum who experienced severe gastrointestinal bleeding after five days of cefoperazone treatment post-surgery.
Article Abstract
Cefoperazone is a parenteral third generation cephalosporin which is active against many Gram positive and Gram negative organisms. Cefaperazone, like other cephalosporins which contain methyltiotetrazole side chain, can cause hypoprotrombinaemia and bleeding problems. Here we report a nine-year old child with Meckel's diverticulum who had cefoperazone induced massive gastrointestinal bleeding on the fifth day following the operation.
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| http://dx.doi.org/10.1080/00015458.2008.11680339 | DOI Listing |
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