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Exposome-Wide Association Study of Thyroid Function Using U.S. National Health and Nutrition Examination Survey Data.
Environ Res
January 2025
Department of Environmental Science, Baylor University, Waco, TX, USA.
Previous epidemiologic studies examining thyroid function and chemical exposures have typically focused on a single or a limited number of chemical classes, often neglecting the effects of chemical mixtures. This study addressed this gap by exploring the associations between exposure to hundreds of chemicals and thyroid function using an exposome-wide association study (ExWAS) approach and National Health and Nutrition Examination Survey (NHANES) data. We analyzed data from three NHANES cycles (2007-2008, 2009-2010, 2011-2012), which include measures of thyroid function (free and total triiodothyronine [T3], free and total thyroxine [T4], thyroid-stimulating hormone [TSH]) and chemical biomarker concentrations from 9,082 participants.
View Article and Find Full Text PDFGOLD grade-specific characterization of COPD in the COSYCONET multi-center trial: comparison of semiquantitative MRI and quantitative CT.
Eur Radiol
January 2025
Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany.
Objectives: We hypothesized that semiquantitative visual scoring of lung MRI is suitable for GOLD-grade specific characterization of parenchymal and airway disease in COPD and that MRI scores correlate with quantitative CT (QCT) and pulmonary function test (PFT) parameters.
Methods: Five hundred ninety-eight subjects from the COSYCONET study (median age = 67 (60-72)) at risk for COPD or with GOLD1-4 underwent PFT, same-day paired inspiratory/expiratory CT, and structural and contrast-enhanced MRI. QCT assessed total lung volume (TLV), emphysema, and air trapping by parametric response mapping (PRM, PRM) and airway disease by wall percentage (WP).
Blood pressure in women in the First National Survey of Health and Nutrition of Indigenous Peoples in Brazil.
Cien Saude Colet
December 2024
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz. Rio de Janeiro RJ Brasil.
Estimating average blood pressure levels and prevalence of arterial hypertension (AH) and associated factors is essential to monitoring health and planning actions to combat noncommunicable diseases (NCDs) in Indigenous peoples in Brazil. This is a cross-sectional study that investigated average blood pressure levels and prevalence of arterial hypertension in 4,680 Indigenous women (aged 18-49 years), using data from the 1st National Survey of Health and Nutrition of Indigenous Peoples (2008-2009) and associated factors, such as through gamma regression and multilevel logistics. The prevalence of hypertension was 10.
View Article and Find Full Text PDFAssociations between tooth loss, denture use, and dementia in older Taiwanese adults.
J Chin Med Assoc
January 2025
Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.
Background: The literature has mainly focused on the association between tooth loss and dementia, and evidence regarding the separate and joint effects of tooth loss and denture use on the risk of dementia is limited. This study investigated the links among tooth loss, denture use, and dementia risk in Taiwanese adults aged 65 years or older.
Methods: This retrospective cohort study utilized data from the 2009 National Health Interview Survey and 2008-2017 National Health Insurance claim records, including the records of 2247 individuals free from dementia treatment in 2008-2009.
Food Colors' Dietary Exposure in the Brazilian Population Using the 2008-2009 and 2017-2018 POF Food Consumption Databases.
Foods
December 2024
Faculdade de Engenharia de Alimentos, Universidade Estadual de Campinas, Cidade Universitária, R. Monteiro Lobato 80, Campinas 13083-862, Brazil.
Two out of the four steps of risk assessment for chemical substances in food, i.e., exposure assessment and risk characterization, merit regional evaluation based on current legislation and local food consumption data.
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