Acute nonvariceal gastrointestinal bleeding is the most common emergency managed by endoscopists and the endoscopic therapy has generally been recommended as the first-line treatment. Traditionally, endoscopic treatment included injections of epinephrine and sclerosing solutions or the use of thermocoagulation. In the last decade with the introduction of hemoclips and band ligators, we have witnessed a significant improvement in the clinical outcome of nonvariceal gastrointestinal bleeding. Endoclipping is a safe and effective technique that contributes to hemostasis of bleeding lesions of the gastrointestinal tract.
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ABC score is a better predictor for 30-day mortality in upper gastrointestinal bleeding: A prospective single-center study.
Indian J Gastroenterol
December 2024
Department of Gastroenterology and Hepatology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, 576 104, India.
Article Synopsis
- Acute upper gastrointestinal bleeding (UGIB) has a significant mortality rate of around 10%, and while existing scoring systems exist, none effectively predict mortality outcomes.
- This study conducted in India compared the newly developed ABC score, based on age, blood tests, and comorbidities, against other pre-existing scoring systems to assess its effectiveness in predicting mortality.
- Results showed the ABC score had the highest accuracy (AUROC of 0.75) in predicting 30-day mortality, particularly showing better performance in patients with variceal bleeding compared to non-variceal bleeding.
Trends for Admission, Mortality and Emergency Surgery in Upper Gastrointestinal Bleeding: A Study of Eight Years of Admissions in a Tertiary Care Hospital.
Int J Gen Med
December 2024
Surgery Department, University of Medicine and Pharmacy of Craiova, Craiova, Romania.
Introduction: Most studies have shown a declining incidence of upper gastrointestinal bleeding (UGIB) in recent years. Data regarding mortality were controversial; in non-variceal bleeding, the increasing age of the population, increased use of anti-thrombotic and anticoagulant therapy in patients with cardiovascular diseases, and the use of non-steroidal anti-inflammatory drugs are counterbalanced by the progress in endoscopic therapy with stable mortality.
Material And Method: We performed a retrospective, cross-sectional study that included patients admitted with UGIB in Clinical Emergency Hospital Craiova during 2013-2020.
Clinical landscape and treatment of acute non-variceal upper gastrointestinal bleeding: Insights from a high-volume center in Shaanxi, China.
World J Clin Cases
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Department of General Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome 00128, Italy.
Article Synopsis
- The article discusses a recent study by Wang on acute non-variceal upper gastrointestinal bleeding (ANVUGIB), a serious gastroenterological emergency.
- The research analyzed over 530 patients at a high-volume center in Shaanxi, China, revealing a younger patient demographic and a greater prevalence of gastric and duodenal ulcers compared to European studies.
- It underscores the significance of endoscopic treatment as the preferred management approach and the need to follow current guidelines for effective treatment of ANVUGIB.
Rates, Risk Factors, and Outcomes of Nonvariceal Upper Gastrointestinal Bleeding in Patients Hospitalized for COVID-19 in the United States.
Curr Med Sci
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Department of Medicine, University of Minnesota/Minneapolis VA Medical Center, Minneapolis, 55417, USA.
Article Synopsis
- The study looked at how often and why non-variceal upper gastrointestinal bleeding (NVUGIB) occurs in hospitalized COVID-19 patients, as well as the impact of this condition on patient outcomes.
- Among over a million hospitalized patients, 1.87% experienced NVUGIB, with Asian Americans at the highest risk followed by other racial groups, and patients with higher Charlson Comorbidity Index scores also faced increased risk.
- COVID-19 patients who developed NVUGIB had significantly worse outcomes, including much higher rates of mortality and severe complications like kidney injury and cardiac arrest, highlighting the need for better prevention strategies.
Author Correction: Comparison and validation of several scoring systems for non-variceal upper gastrointestinal bleeding: a retrospective study.
Sci Rep
December 2024
Division of Gastroenterology, Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, 282 Munhwa-ro Jung-gu, Daejeon, 35015, South Korea.
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