The character of changes of rat bone marrow (BM) erythroblastic islets (EI) was studied in different periods after III degree burn of 15% body surface. Marked differences in the qualitative EI composition were revealed in the cortical generative zone and the central maturation zone of control animals. Proliferative EI forms predominated in the generative zone and involute EI in the maturation zone. The absolute number of EI in BM reduced in the early period of burn anaemia, probably due to proteolysis mainly through a decrease of involute EI in the maturation zone. The number of EI in BM reached minimal level in the late period of burn anaemia. Inhibition of erythropoiesis in the EI was manifested by a decrease in the content of proliferating forms of EI predominantly in the BM generative zone, probably due to slower involvement of erythroid CFU cells in erythropoiesis and inhibition of specific functions of EI macrophages.
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